Interlobar collateral ventilation impacts EB valve outcomes

Interlobar collateral ventilation impacts EB valve outcomes

(HealthDay)—A more careful selection of patients could help improve the success rate of bronchoscopic lung-volume reduction with the use of one-way endobronchial valves in patients with emphysema, according to a study published in the Dec. 10 issue of the New England Journal of Medicine.

The researchers randomly assigned 68 patients with severe , average age 59, and confirmed absence of collateral ventilation to bronchoscopic endobronchial-valve treatment (EBV group) or to a control group who received continuing standard medical care. The team assessed changes in forced expiratory volume in one second (FEV1), forced vital capacity (FVC), and six-minute walk distance from baseline to six months.

The researchers found greater improvements for those in the EBV group. Seventy-five percent of the patients who got the devices responded to the treatment, study coauthor Dirk-Jan Slebos, M.D., Ph.D., an associate professor with the department of pulmonary diseases at the University of Groningen in the Netherlands, told HealthDay.

"Endobronchial-valve treatment significantly improved and exercise capacity in with severe emphysema characterized by an absence of interlobar collateral ventilation," the authors conclude.

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Journal information: New England Journal of Medicine

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Citation: Interlobar collateral ventilation impacts EB valve outcomes (2015, December 10) retrieved 28 March 2024 from https://medicalxpress.com/news/2015-12-interlobar-collateral-ventilation-impacts-eb.html
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