Summer concentrations of 25OHD predict bone mineral density

Summer concentrations of 25OHD predict bone mineral density

(HealthDay)—Summer levels of serum 25-hydroxyvitamin D (S-25OHD) are associated with bone mineral density of the total hip, according to a study published online Sept. 25 in the Journal of Internal Medicine.

Karl Michaëlsson, M.D., from Uppsala University in Sweden, and colleagues examined the relative importance of S-25OHD for by season in a subcohort of 5,002 Swedish women randomly selected from a large population-based cohort.

The researchers found that there was a gradual increase in bone mineral density of the total hip in samples collected during summer, up to an S-25OHD level of 40 nmol L−1. Compared to those with S-25OHD levels above 80 nmol L−1, adjusted bone mineral density was 11 percent lower in women with S-25OHD concentrations below 30 nmol L−1 and 6 percent lower in those with S-25OHD concentrations 30 to 40 nmol L−1 during summer. Compared with concentrations above 80 nmol L−1, low S-25OHD concentrations (<30 nmol L−1) during summer correlated with increased adjusted relative risk of osteoporosis. There were no differences in mean bone mineral density values between categories of S-25OHD in winter.

"To determine an S-25OHD cut-off level for vitamin D deficiency, it may be necessary to take into account the season of blood collection," the authors write.

More information: Full Text

Journal information: Journal of Internal Medicine

Copyright © 2016 HealthDay. All rights reserved.

Citation: Summer concentrations of 25OHD predict bone mineral density (2016, October 4) retrieved 29 March 2024 from https://medicalxpress.com/news/2016-10-summer-25ohd-bone-mineral-density.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.

Explore further

Swedish researchers show impact of long-term vitamin D insufficiency on fracture risk

 shares

Feedback to editors