Agency for Science, Technology and Research (A*STAR), Singapore
How connections in the brain must change to form memories could help to develop artificial cognitive computers
Exactly how memories are stored and accessed in the brain is unclear. Neuroscientists, however, do know that a primitive structure buried in the center of the brain, called the hippocampus, is a pivotal region ...
Neuroscience
Nov 07, 2012 |
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Scientists discover mechanism that controls obesity, atherosclerosis and potentially cancer
Scientists from the Institute of Molecular and Cell Biology (IMCB) have discovered a new signalling pathway that controls both obesity and atherosclerosis. The team demonstrated, for the first time, that mice deficient in ...
Medical research
Jul 03, 2012 |
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New research sheds light on the molecular mechanisms by which a virus contributes to cancer
Hepatocellular carcinoma (HCC) is the third leading cause of cancer deaths worldwide and is associated with exposure to hepatitis B virus (HBV). Patients carrying the virus have a 100-fold greater risk of ...
Cancer
Aug 29, 2012 |
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A single enzyme plays a critical role in helping the body effectively fight viral infection
The body’s initial response to invading bacteria or viruses is mediated by the innate immune system, wherein cells secrete signaling factors called cytokines that promote inflammation and stimulate a ...
Immunology
Aug 15, 2012 |
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Singapore scientists find genes associated with glaucoma
Singapore scientists have identified three new genes associated with Primary Angle Closure Glaucoma (PACG), a leading cause of blindness in Chinese people. PACG affects 15 million people worldwide, 80% of whom live in Asia.
Genetics
Sep 03, 2012 |
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Potential drug for treating deadly brain cancer
(Medical Xpress)—A*STAR scientists have identified a biomarker of the most lethal form of brain tumours in adults − glioblastoma multiforme. The scientists found that by targeting this biomarker and depleting ...
Cancer
Sep 04, 2012 |
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Recently uncovered human counterparts to a subset of mouse immune cells may enable better vaccination strategies
Mice have made an immeasurable contribution to medicine and our overall understanding of human disease. This animal model is not without its limitations, however, and scientists are continually learning about ...
Medical research
Oct 24, 2012 |
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Recently discovered stem cell population could one day provide useful source material for kidney repair
Within every human kidney, millions of filtration units known as nephrons are hard at work clearing metabolic waste products from the blood. Given the dirty work they perform, one might expect that the cells ...
Medical research
Nov 07, 2012 |
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Researchers identify four distinct mechanisms that contribute to gastric cancers
Scientists at A*STAR's Genome Institute of Singapore (GIS) headed a study that discovered four processes by which gastric cancer is formed. This is extremely important since gastric cancer is the second most common cause ...
Cancer
Jan 28, 2013 |
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Scientists discover 'switch' critical to wound healing
Patients with diseases such as diabetes suffer from painful wounds that take a long time to heal, making them more susceptible to infections that could even lead to amputations. A*STAR's discovery paves the way for therapeutics ...
Medical research
Mar 08, 2013 |
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Artificial human livers engineered for drug testing and discovery
The liver is an important target organ for drug testing because all drugs pass through it for detoxification. This is a process whereby harmful substances are reduced or removed from the body. Drugs that cannot be detoxified ...
Medical research
Mar 15, 2013 |
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Insights into an abnormally edited RNA molecule may yield new weapons against a hard-to-kill cancer
Diagnosis of the brain cancer glioblastoma multiforme (GBM) is particularly bad news for patients due to limited available medical options and poor outcomes. Even treatments that can eliminate other malignancies, ...
Cancer
Apr 10, 2013 |
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Scientists discover 'switch' to boost anti-viral response to fight infectious diseases
Singapore scientists from Bioprocessing Technology Institute (BTI) under the Agency of Science, Technology and Research (A*STAR) have for the first time, identified the molecular ‘switch’ that directly triggers ...
Medical research
May 11, 2012 |
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Scientists unravel mechanism that causes liver cancer
Scientists at the Genome Institute of Singapore (GIS) have unraveled the mechanism that causes liver cancer (hepatocellular carcinoma, HCC), one of the most common solid tumors worldwide. This genome-wide research was done ...
Genetics
May 28, 2012 |
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Microfibers help virus fool the body's immune system
A key challenge in virus-based gene therapy is avoiding detection by the human immune system so that the virus would not be deactivated before it reaches its intended target. Now, researchers at the Institute ...
Medical research
Jul 31, 2012 |
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