Amyloids, or fibrous aggregates of abnormally folded proteins, are a common feature in degenerative diseases such as Alzheimer's, diabetes and cancer. Amyloids occur naturally in the body, but despite decades ...
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A*STAR scientists have identified the enzyme, telomerase, as a cause of chronic inflammation in human cancers. Chronic inflammation is now recognized as a key underlying cause for the development of many human cancers, autoimmune ...
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Exactly how memories are stored and accessed in the brain is unclear. Neuroscientists, however, do know that a primitive structure buried in the center of the brain, called the hippocampus, is a pivotal region ...
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Neural stem cells are the precursors of cells in the nervous system. As well as being crucial for early development, they are present throughout life, contributing to flexibility and repair of the nervous ...
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Mice have made an immeasurable contribution to medicine and our overall understanding of human disease. This animal model is not without its limitations, however, and scientists are continually learning about ...
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(Medical Xpress)—A*STAR scientists have identified a biomarker of the most lethal form of brain tumours in adults − glioblastoma multiforme. The scientists found that by targeting this biomarker and depleting ...
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Singapore scientists have identified three new genes associated with Primary Angle Closure Glaucoma (PACG), a leading cause of blindness in Chinese people. PACG affects 15 million people worldwide, 80% of whom live in Asia.
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Scientists at A*STAR’s Institute of Medical Biology (IMB), in collaboration with doctors and scientists in Jordan, Turkey, Switzerland and USA, have identified the genetic cause of a birth defect known as Hamamy syndrome. ...
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Though it originates from the body's own cells, a tumor is as much of a hostile invader as any virus or bacterium. If the immune system is sufficiently sensitized, it can mount a counterattack just as it ...
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Sustained low-grade inflammation and an above-average appetite are commonly found in obese individuals. Therefore, it seems counterintuitive that the acute inflammation associated with many illnesses normally ...
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A Singaporean computer scientist and his American colleague have created a computer simulation of how humans perform on a widely employed test of implicit or unconscious social attitudes, particularly racial ...
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Changes in the pattern of connections in the resting brain predict the extent to which stroke patients will recover following rehabilitation, according to new research led by Cuntai Guan of the A*STAR Institute ...
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Singapore's Agency for Science, Technology and Research (A*STAR) and Switzerland's Cytos Biotechnology AG today announced that the first healthy volunteer has been dosed in a Phase 1 clinical trial with their ...
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A tumor is not a uniform mass of identical cells. However, teasing apart genetic heterogeneity within a biopsied tumor can be difficult. Researchers often fail to tell the difference between a rare variant ...
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The eye is covered by a clear and protective layer called the cornea, and abnormal thickness of the cornea can result in eye disease. An international research team including Chiea Chuen Khor of the A*STAR ...
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