When the pathogen-sensing intracellular receptors TLR-7 and TLR-9 were implicated in systemic lupus erythematosus (SLE), it was suspected that their removal would lessen the severity of the disease. However, while this held ...
Feb 4, 2019
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Researchers at A*STAR's Singapore Bioimaging Consortium (SBIC) have discovered that branched-chain amino acids (BCAAs) in tumours can be targeted to prevent and treat cancer. Together with collaborators from the United States ...
Jan 22, 2019
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The transformation of embryonic stem cells, and their induced pluripotent counterparts into potentially limitless supplies of new heart tissue has been hindered by a lack of consistency from one stem cell line to the next, ...
Jan 15, 2019
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An antibody that targets and is taken up only by certain types of cancer cells has been developed by A*STAR researchers. Combining this antibody with an anticancer drug could lead to a new treatment for some types of breast ...
Jan 15, 2019
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After a flesh wound, skin cells march forward to close the gap and repair the injury. Findings from a team led by Leah Vardy at A*STAR's Skin Research Institute of Singapore now demonstrate how a carefully regulated set of ...
Jan 15, 2019
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White blood cells, also known as monocytes, play a key role in the immune system's response to infection. They have been shown to fuse and form multinucleated giant cells (MGCs) during inflammatory reactions, or in response ...
Jan 15, 2019
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Scientists from A*STAR's Singapore Immunology Network (SIgN) and clinicians from Singapore's National University Hospital (NUH) have found that when it comes to influenza vaccinations, healthy elderly individuals are able ...
Dec 20, 2018
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The protein thrombin is vital for ensuring blood coagulates in a wound, but new research suggests small fragments of it, called thrombin-derived C-terminal peptides (TCPs), could also decrease the risk of sepsis in response ...
Dec 20, 2018
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Switching off the enzyme that adds protective caps to chromosome ends could help fight many types of cancer, A*STAR researchers have shown. The team demonstrated the treatment's potential by using it to thwart tumor growth ...
Dec 20, 2018
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Small RNA molecules in saliva could be used to detect the virus that causes hand, foot and mouth disease, enabling early intervention to limit spread of the infection.
Dec 20, 2018
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