Baylor College of Medicine

Genomic architecture presages genomic instability: study

When cells divide normally, DNA gets copied perfectly and distributed among the daughter cells with an even hand. Occasionally though, DNA breaks during division and is rearranged, resulting in duplications or deletions of ...

Oct 02, 2011
popularity 5 / 5 (2) | comments 0 | with audio podcast

'Moonlighting' enzyme unravels arginine paradox

(Medical Xpress) -- Nearly 20 years ago, the journal Science tagged nitric oxide as the "molecule of the year." Since that time, researchers have tried to study and target this simple molecule that is involved in virtually every ...

Nov 13, 2011
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Notch1 and osteoblasts play role in bone cancer initiation

(Medical Xpress)—A new mouse model of osteogenic sarcoma, a potentially deadly form of bone cancer, shows that high levels of Notch1, a gene that helps determine cell fate, can drive osteoblasts (cells that normally lead ...

Sep 08, 2014
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Study shows epigenetic changes can drive cancer

Cancer has long been thought to be primarily a genetic disease, but in recent decades scientists have come to believe that epigenetic changes – which don't change the DNA sequence but how it is 'read' – also play a role ...

Jul 26, 2014
popularity 4.9 / 5 (8) | comments 2

TopBP1 a sweet spot for treatment in multiple cancers

A compound called calcein may act to inhibit topoisomerase IIβ-binding protein 1 (TopBP1), which enhances the growth of tumors, said researchers from Baylor College of Medicine in a report that appears online in the journal ...

Nov 17, 2014
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