In a landmark study, researchers from the Broad Institute and Massachusetts General Hospital reveal a completely new biological mechanism that underlies cancer. By studying brain tumors that carry mutations in the isocitrate ...
Dec 23, 2015
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29
Of the thousands of species of bacteria that live in the digestive tract, scientists know how only a handful of them directly influence human health. Now, researchers at the Broad Institute of MIT and Harvard and Harvard ...
Jun 16, 2020
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193
Psychiatric disorders such as schizophrenia and bipolar disorder often run in families. In a new international collaboration, researchers explored the genetic connections between these and other disorders of the brain at ...
Jun 21, 2018
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126
An analysis of nearly 3,800 colorectal cancer patients—the largest germline risk study for this cancer to date—reveals opportunities for improved risk screening and, possibly, treatment.
Feb 23, 2018
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82
Researchers have generated a cellular atlas of the mouse brain, based on the gene expression profiles of nearly 700,000 individual cells covering nine major brain regions.
Aug 10, 2018
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75
Most patients diagnosed with type 2 diabetes are treated with a "one-size-fits-all" protocol that is not tailored to each person's physiology and may leave many cases inadequately managed. A new study by scientists at the ...
Sep 21, 2018
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122
Inflammatory bowel diseases are chronic, painful disorders of the intestine that afflict roughly 1.5 million people in the United States. Yet the underlying mechanisms of these diseases, which include ulcerative colitis and ...
Jul 26, 2019
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30
In a landmark genetic study of more than 121,000 people, an international consortium called SCHEMA, led by researchers at the Broad Institute of MIT and Harvard, has identified extremely rare protein-disrupting mutations ...
Apr 6, 2022
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148
Unleashing the immune system to fight tumors—an approach enabled by immunotherapy—has led to remarkable outcomes in some cancer patients, but in many more, cancer cells evade the treatment and continue to spread. Now, ...
Nov 2, 2018
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64
More children die of brain tumors than any other type of cancer. Diffuse midline gliomas (DMGs) are a particularly deadly kind, and are difficult to treat with drugs or surgery because they're in an important part of the ...
Feb 4, 2022
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