Over the last 15 years, researchers at the Stanley Center for Psychiatric Research at the Broad Institute of MIT and Harvard have been working to decode the biological causes of schizophrenia, which affects 20 million people ...
Apr 7, 2022
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When treating a cancer patient, oncologists aim to predict the course of the patient's disease to make critical treatment decisions. Knowing a tumor's unique molecular signature can help guide these decisions by providing ...
Sep 23, 2021
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A study of gut microbes from more than 400 children points to how the microbiome behaves in this inflammatory bowel disease.
Oct 11, 2018
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Scientists have long known that the complement cascade, a set of immune system proteins, protects against infection in the body. But in recent years, researchers have uncovered new roles for the system in the brain, including ...
Mar 30, 2023
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Most Alzheimer's disease research on human brain tissue has studied postmortem samples, making it difficult for scientists to discern the earliest events in the brain that might have triggered the buildup of plaques and the ...
Sep 29, 2023
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New study finds that a type of genetic modification involving long, repeated sequences within the human genome can affect a variety of health-related traits.
Sep 24, 2021
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Polygenic scores can predict a person's risk for conditions like coronary artery disease, breast cancer, and type 2 diabetes (T2D) with great accuracy, even in patients who lack common warning signs. This new genome analysis ...
Mar 29, 2019
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Patients with bacterial infections who are promptly diagnosed and treated with the most effective antibiotic fare better than those who wait. But current methods of identifying which drug will kill the pathogen take days ...
Nov 27, 2019
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An international consortium of scientists has analyzed protein-coding genes from nearly 46,000 people, linking rare DNA alterations to type 2 diabetes. The study, one of the largest known of its type, includes data from people ...
May 22, 2019
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A team of researchers at the Broad Institute of MIT and Harvard has developed a new approach to next-generation sequencing that detects genetic mutations within single molecules of DNA.
Apr 28, 2023
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