One of the newest types of cancer drugs, immunotherapies called immune checkpoint inhibitors, has transformed the treatment of lung cancer over the last decade—dramatically improving the survival of some patients with the ...
Apr 19, 2023
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Much of the research on new cancer treatments in the last two decades has focused on genetic targets that allow cancers to grow and spread by altering cell signaling or shutting off tumor suppressors. There is a growing body ...
Apr 7, 2023
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Scientists have long known that the complement cascade, a set of immune system proteins, protects against infection in the body. But in recent years, researchers have uncovered new roles for the system in the brain, including ...
Mar 30, 2023
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Late last year, thousands of children across the United States were hospitalized with respiratory syncytial virus (RSV), but unlike previous RSV surges, this one affected a larger number of people and a broader range of age ...
Feb 23, 2023
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Researchers at the Broad Institute of MIT and Harvard and Massachusetts General Hospital have constructed a high-resolution cellular map of Crohn's disease, a chronic condition in which a hyperactive immune system causes ...
Jan 31, 2023
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Many diseases affect how cells are spatially organized in tissues, such as in Alzheimer's disease, where amyloid-β proteins clump together to form plaques in the brain. Studying how cells differ in various regions of tissue ...
Dec 8, 2022
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Over the past 15 years, more than 200 sites in the human genome have been linked to risk for coronary artery disease (CAD), the leading cause of death worldwide. Still, researchers don't fully understand how those genomic ...
Dec 7, 2022
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Gene therapies can treat, even potentially cure, certain genetic diseases, but it is challenging to deliver the treatments to the parts of the body where they are needed. Researchers have engineered viruses called adeno-associated ...
Nov 22, 2022
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Less than 2% of the human genome is made up of genes that code for proteins, with the remaining 98% being non-coding and involved in regulating gene expression. Scientists have found many changes in the coding region of the ...
Oct 25, 2022
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Organoids are carefully grown collections of cells in a dish, designed to mimic organ structures and composition better than conventional cell cultures and give researchers a unique view into how organs such as the brain ...
Sep 30, 2022
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