Brown University

Medical research

Study finds inhibitor for COPD lung destruction

In a new study, a research team based at Brown and Yale implicates a specific mitochondrial protein and pathway in the development of chronic obstructive pulmonary disease (COPD) from exposure to cigarette smoke. Observations ...

Neuroscience

When nerve meets muscle, biglycan seals the deal

A protein that has shown early promise in preventing the loss of muscle function in mouse models of Duchenne muscular dystrophy, has been found in a new study to be a key player in the process of joining nerves to muscles.

Neuroscience

Wireless brain sensor could unchain neuroscience from cables

In a study in the journal Neuron, scientists describe a new high data-rate, low-power wireless brain sensor. The technology is designed to enable neuroscience research that cannot be accomplished with current sensors that ...

Genetics

From DNA to disease, study describes rare, new brain disorder

In rare cases—for instance, among siblings in two families from Pakistan and Oman described in a new study—children have been born with an unnamed neurological disorder. Now researchers have not only identified the genetic ...

Oncology & Cancer

Suppressing a protein reduces cancer spread in mice

Scientists have found that decreasing the levels of or blocking a specific protein commonly found in humans and many other animals allowed them to slow the spread of two different kinds of cancer to the lungs of mice. The ...

Neuroscience

Autism gene stunts neurons, but growth can be restored, in mice

Brown University researchers have traced a genetic deficiency implicated in autism in humans to specific molecular and cellular consequences that cause clear deficits in mice in how well neurons can grow the intricate branches ...

Medical research

Formaldehyde damages proteins, not just DNA

The capacity of formaldehyde, a chemical frequently used in manufactured goods such as automotive parts and wood products, to damage DNA, interfere with cell replication and cause cancer inspired new federal regulations this ...

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