Charité - Universitätsmedizin Berlin

Oncology & Cancer

Exploring tumor evolution

Tumors are heterogeneous, which means that different parts of the same tumor can be genetically distinct. This phenomenon, known as intratumor heterogeneity, is steadily gaining in significance within the field of cancer ...

Diseases, Conditions, Syndromes

SARS-CoV-2 disrupts timing of immune response

Once an infection is under control, the body normally uses a biochemical messenger known as TGFβ to downgrade its immune response. In severe COVID-19, however, this messenger is released at the very beginning of the infection, ...

Neuroscience

Hungry or full: It comes down to the atomic details

A protein—measuring just a few nanometers in size—acts as a molecular switch with a crucial role in determining whether we feel hungry or full. By determining of the protein's 3-D structure, researchers from Charité ...

Cardiology

Progress for patients with weak hearts

Until now, patients with heart failure with preserved ejection fraction—the most common type of heart failure in the elderly—have had no access to evidenced-based treatments. For the first time, a large clinical trial ...

Neuroscience

Structuring the cerebral neocortex

The neocortex is a layered structure of the brain in which neurons are arranged parallel to each other. This organization is critical for healthy brain function. A team of researchers from Charité - Universitätsmedizin ...

Overweight & Obesity

Dieting and its effect on the gut microbiome

Researchers from Charité–Universitätsmedizin Berlin and the University of California in San Francisco were able to show for the first time that a very low calorie diet significantly alters the composition of the microbiota ...

Medical research

Using a tapeworm drug against SARS-CoV-2?

Researchers from the German Center for Infection Research (DZIF) at Charité - Universitätsmedizin Berlin and the University of Bonn have examined the way in which SARS-CoV-2 reprograms the metabolism of the host cell in ...

Diseases, Conditions, Syndromes

Why do we continue to see outbreaks of SARS-CoV-2 in care homes?

SARS-CoV-2 outbreaks involving care homes with fully vaccinated residents have been reported across Germany. In order to gain a better understanding of this phenomenon, a team of researchers from Charité - Universitätsmedizin ...

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