Children's Hospital Boston

Oncology & Cancer

How a leukemia hijacks the genes needed by blood stem cells

As a child, Lynn Aureli didn't know that a particular genetic change contributed to her acute myeloid leukemia (AML)—an alteration that eventually would help explain the cancer's lack of response to chemotherapy. Nor was ...

Oncology & Cancer

Earlier detection of a malignancy in neurofibromatosis type 1

Neurofibromatosis type 1 (NF1) is a common genetic condition, affecting 1 in 3,000 individuals, and people with NF1 are at greater risk of developing a rare, aggressive form of cancer. Diagnosing malignant peripheral nerve ...

Oncology & Cancer

Obesity is increasing people's risk of cancer. Why?

Obesity is now a global epidemic, and it is increasing people's risk for cancer. The National Cancer Institute lists more than a dozen cancers that are associated with overweight and obesity. But how obesity increases cancer ...

Neuroscience

Why does fasting reduce seizures?

Calorie restriction has long been associated with reduced seizures in epilepsy. New research from Boston Children's Hospital helps explain how fasting affects neurons in the brain and could lead the way to new approaches ...

Psychology & Psychiatry

Psychotic symptoms in children may have a genetic cause

A 6-year-old boy began hearing voices coming from the walls and the school intercom telling him to hurt himself and others. He saw ghosts, aliens in trees, and colored footprints. Joseph Gonzalez-Heydrich, MD, a psychiatrist ...

Diseases, Conditions, Syndromes

Powerful new antibody neutralizes all known SARS-CoV-2 variants

As SARS-CoV-2 has evolved and mutated, therapeutic antibodies that worked early in the pandemic have become less effective, and newer variants, especially omicron, have developed ways to evade the antibodies we make in response ...

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