Children's Hospital Boston

Medical research

An 'atlas' of the brain's choroid plexus across the lifespan

Once viewed merely as a producer of the cerebrospinal fluid (CSF) bathing the brain and spinal cord, the choroid plexus is now known to be a key player in brain development and immunity. These fronds of brain tissue, located ...

Pediatrics

Piecing together the preterm infant microbiome

The human microbiome—the collection of microbes living in the gut—is now recognized as an important contributor to health and disease. The environment, the host, and microbe-microbe interactions are all likely to shape ...

Neuroscience

Predicting pediatric seizures with a wristband

The ability to track seizures has a number of potential benefits: It could allow physicians to better determine optimal dosing and timing of medication, as well as enable timely interventions to help prevent impending seizures. ...

Neuroscience

'Mosaic' gene mutations could explain some cases of autism

The causes of autism remain mysterious. Scientists have linked autism spectrum disorder to a long list of genes, but most children with autism have no known explanation. Two new studies add to the picture, implicating mutations ...

Genetics

Advances in understanding autism, based on "mosaic" mutations

Two studies in today's Nature Neuroscience, led by researchers at Boston Children's Hospital, Brigham and Women's Hospital (BWH), and Harvard Medical School (HMS), implicate mosaic mutations arising during embryonic development ...

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