Children's Hospital of Philadelphia

Survey of ER docs and pediatricians highlights need for training, tools to manage kids' concussions

While general pediatricians and pediatric emergency physicians value their role in concussion management, a study of their self-reported knowledge, practices and attitudes points to the need for improved concussion-specific ...

Pediatrics created Nov 12, 2012 | popularity not rated yet | comments 0

New genes discovered for adult BMI levels

A large international study has identified three new gene variants associated with body mass index (BMI) levels in adults. The scientific consortium, numbering approximately 200 researchers, performed a meta-analysis of 46 ...

Genetics created Oct 25, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Engaging parents leads to better treatments for children with adhd

Pediatricians and researchers at The Children's Hospital of Philadelphia's(CHOP) have developed a first-of-its kind tool to help parents and health care providers better treat ADHD (attention deficit-hyperactivity disorder). ...

Attention deficit disorders created Oct 23, 2012 | popularity not rated yet | comments 0

Greater parental stress linked to children's obesity, fast food use and reduced physical activity

Parents with a higher number of stressors in their lives are more likely to have obese children, according to a new study by pediatric researchers. Furthermore, when parents perceive themselves to be stressed, their children ...

Pediatrics created Oct 22, 2012 | popularity not rated yet | comments 0 | with audio podcast

Large international study finds 21 genes tied to cholesterol levels

In the largest-ever genetic study of cholesterol and other blood lipids, an international consortium has identified 21 new gene variants associated with risks of heart disease and metabolic disorders. The findings expand ...

Genetics created Oct 11, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Newborn mortality was higher for several years after large-scale closures of urban maternity units

After a series of Philadelphia hospitals started closing their maternity units in 1997, infant mortality rates increased by nearly 50 percent over the next three years. The mortality rates subsequently leveled off to the ...

Health created Oct 03, 2012 | popularity not rated yet | comments 0

New gene variants raise risk of neuroblastoma, influence tumor progression

Researchers have discovered two gene variants that raise the risk of the pediatric cancer neuroblastoma. Using automated technology to perform genome-wide association studies on DNA from thousands of subjects, the study broadens ...

Genetics created Sep 04, 2012 | popularity not rated yet | comments 0 | with audio podcast

Cornelia deLange syndrome: Mutations disrupt cellular recycling and cause childhood genetic disease

Genetics researchers have identified a key gene that, when mutated, causes the rare multisystem disorder Cornelia deLange syndrome (CdLS). By revealing how mutations in the HDAC8 gene disrupt the biology of proteins that ...

Genetics created Aug 12, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

In pilot study, a peptide controls blood sugar in people with congenital hyperinsulinism

A pilot study in adolescents and adults has found that an investigational drug shows promise as the first potential medical treatment for children with the severest type of congenital hyperinsulinism, a rare but potentially ...

Diabetes created Aug 01, 2012 | popularity not rated yet | comments 0

Survival rates for premature babies in high-level NICUs are better than previously reported

Premature babies are more likely to survive when they are born in high-level neonatal intensive care units (NICUs) than in hospitals without such facilities, and this benefit is considerably larger than previously reported.

Pediatrics created Jul 23, 2012 | popularity not rated yet | comments 0

Hospitals in recession-hit areas see uptick in serious cases of child physical abuse

In the largest study to examine the impact of the recession on child abuse, researchers at The Children's Hospital of Philadelphia's (CHOP) PolicyLab detected a significant increase in children admitted to the nation's largest ...

Pediatrics created Jul 16, 2012 | popularity not rated yet | comments 0

Mutations impair childhood growth and development by disrupting organization of chromosome pairs

Researchers studying rare genetic disorders have uncovered insights into those diseases in biological structures that regulate chromosomes when cells divide. Focusing on the cohesin complex, a group of proteins ...

Genetics created May 29, 2012 | popularity not rated yet | comments 0 | with audio podcast

Children with cancer have complete responses in a Children's Oncology Group phase 1 trial

A pill designed to zero in on abnormal genes that drive specific cancers has produced encouraging early results in children with an uncommon but aggressive type of lymphoma, as well as in children with a rare form of neuroblastoma.

Cancer created May 17, 2012 | popularity not rated yet | comments 0

Erectile dysfunction drug may benefit cardiac function in young patients with heart defects

Sildenafil, also known as the erectile dysfunction drug Viagra, may give a boost to underdeveloped hearts in children and young adults with congenital heart defects. Researchers from The Children's Hospital of Philadelphia ...

Cardiology created May 08, 2012 | popularity not rated yet | comments 0 | with audio podcast

Protein may represent a switch to turn off B cell lymphoma

Researchers studying the molecular signals that drive a specific type of lymphoma have discovered a key biological pathway leading to this type of cancer. Cancerous cells have been described as being "addicted" to certain ...

Cancer created May 07, 2012 | popularity 5 / 5 (1) | comments 0