Children's Hospital of Philadelphia

New research expands understanding of psychoactive medication use among children in foster care

A few months after the federal Government Accountability Office (GAO) issued a report on the use of psychoactive drugs by children in foster care in five states, a national study from PolicyLab at The Children's Hospital ...

Health created Apr 30, 2012 | popularity 5 / 5 (1) | comments 0

Teen seat belt use is significantly higher in states with stronger laws

While most teens do buckle up when driving, new research shows that novice teen drivers who live in states with so-called "secondary enforcement" seat belt laws are less likely to use the life-saving devices than those in ...

Health created Apr 19, 2012 | popularity not rated yet | comments 0

Largest-ever genome-wide study identifies genes for common childhood obesity

Genetics researchers have identified at least two new gene variants that increase the risk of common childhood obesity.

Genetics created Apr 08, 2012 | popularity not rated yet | comments 0 | with audio podcast

In children born with severe heart defect, surgical management has little effect on neuro outcomes

In the largest multicenter clinical trial of children undergoing early-stage surgery for single-ventricle heart defects, differences in intraoperative management did not significantly affect neurodevelopmental outcomes at ...

Cardiology created Apr 05, 2012 | popularity 4.5 / 5 (2) | comments 0

Delay in surgery can cause irreparable meniscus tears in children with ACL injuries

For children aged 14 and under, delaying reconstructive surgery for anterior cruciate ligament (ACL) injuries may raise their risk of further injury, according to a new study by pediatric orthopaedic surgeons. If surgery ...

Surgery created Mar 12, 2012 | popularity not rated yet | comments 0

Sleep breathing machine shows clear benefits in children with sleep apnea

Children and adolescents with obstructive sleep apnea had substantial improvements in attention, anxiety and quality of life after treatment with positive airway pressure (PAP)—a nighttime therapy in which a machine ...

Sleep apnea created Feb 10, 2012 | popularity not rated yet | comments 0

Teen passengers: 'The other distraction' for teen drivers

A pair of studies by The Children's Hospital of Philadelphia (CHOP) and State Farm® identify factors that may lead teens to drive with multiple peer passengers and, then, how those passengers may affect their driver's ...

Health created Jan 24, 2012 | popularity not rated yet | comments 0

Newborn screening program aims to help transform treatments for genetic diseases detected at birth

Within the first days of life, screening tests are performed on all newborns born in the U.S. to identify rare and often life-threatening medical conditions that are not apparent at birth. These newborn screening programs ...

Diseases, Conditions, Syndromes created Jan 17, 2012 | popularity not rated yet | comments 0

What to consider when teens with autism want to drive?

In the first study to investigate driving as it relates to teens with a high-functioning autism disorder (HFASD), child development and teen driving experts at The Children's Hospital of Philadelphia's Center for Child Injury ...

Autism spectrum disorders created Jan 09, 2012 | popularity not rated yet | comments 0

How will patients, families and doctors handle the coming flood of personalized genetic data?

Sequencing the entire human genome took more than a decade before leaders of the Human Genome Project announced their completion of a rough draft in a 2000 White House ceremony. Finished in 2003, sequencing that first genome ...

Genetics created Dec 06, 2011 | popularity not rated yet | comments 0

New gene study of ADHD points to defects in brain signaling pathways

Pediatric researchers analyzing genetic influences in attention-deficit/hyperactivity disorder (ADHD) have found alterations in specific genes involved in important brain signaling pathways. The study raises the possibility ...

Attention deficit disorders created Dec 04, 2011 | popularity 4 / 5 (5) | comments 3 | with audio podcast

Crash experts find car seats protect overweight kids, too

Researchers at the Children's Hospital of Philadelphia's Center for Injury Research and Prevention studied nearly 1,000 1- to 8-year-old children involved in crashes and found no evidence of increased injury risk for children ...

Overweight and Obesity created Nov 29, 2011 | popularity not rated yet | comments 0

Basic biology offers clues to better neuroblastoma treatments

By studying tumor biology at the molecular level, researchers are gaining a deeper understanding of drug resistance -- and how to avoid it by designing pediatric cancer treatments tailored to specific mutations in a child's ...

Cancer created Nov 09, 2011 | popularity 3 / 5 (1) | comments 0 | with audio podcast

Animal study suggests that newborn period may be crucial time to prevent later diabetes

Pediatric researchers who tested newborn animals with an existing human drug used in adults with diabetes report that this drug, when given very early in life, prevents diabetes from developing in adult animals. If this finding ...

Diseases, Conditions, Syndromes created Nov 02, 2011 | popularity not rated yet | comments 0 | with audio podcast

Bioengineered protein shows preliminary promise as new therapy for hemophilia

A genetically engineered clotting factor that controlled hemophilia in an animal study offers a novel potential treatment for human hemophilia and a broad range of other bleeding problems.

Genetics created Oct 23, 2011 | popularity not rated yet | comments 0 | with audio podcast