Following two decades of research on a group of rare diseases called hypereosinophilic syndrome at Cincinnati Children's Hospital Medical Center, the U.S. Food and Drug Administration has approved the drug Nucala (mepolizumab) ...
Sep 28, 2020
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Scientists at Cincinnati Children's used human intestinal organoids grown from stem cells to discover how our bodies control the absorption of nutrients from the food we eat. They further found that one hormone might be able ...
Sep 22, 2020
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Scientists who were working on a way to determine the viability of batches of tiny liver organoids have discovered a testing method that may have far broader implications.
Sep 7, 2020
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When girls reach puberty at an unusually early age, they face a significantly higher risk of developing breast cancer later in life. Now, experts at Cincinnati Children's and the University of Cincinnati offer a new, unified ...
Sep 1, 2020
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Scientists studying neuronal energy metabolism found evidence that the loss of an important energy regulator called AMPK in neural stem cells or glial cells called astrocytes causes neuronal death in laboratory rodents. They ...
Sep 1, 2020
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In back-to-back reports published Aug. 27, 2020, in Nature Communications, a team of scientists from Cincinnati Children's and Japan report discoveries that will be vital to a new wave of more-complex organoid development.
Aug 27, 2020
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When children are born with hypoplastic left heart syndrome (HLHS), they require a series of major surgical procedures to survive. But even with a repaired heart, as many as one in four children die from complications before ...
Aug 18, 2020
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A pre-clinical study led by scientists at Cincinnati Children's demonstrates that in mice the drug barasertib reverses the activation of fibroblasts that cause dangerous scar tissue to build up in the lungs of people with ...
Aug 6, 2020
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Many people have understood that our immune systems get weaker as we age, which in part explains why older people often get less protection than younger ones from annual influenza vaccines.
Jul 29, 2020
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A team of international researchers has learned that dose escalation of hydroxyurea treatment for children in Uganda with sickle cell anemia is more effective and has similar side effects than a lower fixed dose of the same ...
Jun 24, 2020
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