Scientists at Cold Spring Harbor Laboratory (CSHL) have created the first mouse model of pancreatic cancer that recreates two subtypes of the human disease. The model, published July 23, 2020 in Cancer Discovery, will help ...
Jul 23, 2020
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Cold Spring Harbor Laboratory (CSHL) Associate Professor Mikala Egeblad and her colleagues describe a newly understood way by which breast cancer cells sabotage a key player in the body's immune system. That key player provides ...
Jul 15, 2020
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A new method developed at Cold Spring Harbor Laboratory (CSHL) uses DNA sequencing to efficiently map long-range connections between different regions of the brain. The approach dramatically reduces the cost of mapping brain-wide ...
Jul 14, 2020
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Scientists at Cold Spring Harbor Laboratory (CSHL) have found that they can stop the growth of pancreatic cancer cells by interfering with the way the cells store cholesterol. Their findings in mice and lab-grown pancreas ...
Jul 7, 2020
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Within the intricate network of cells that make up the brain, chandelier cells stand out for their elaborate, branching structure. With an elegant shape similar to that of its namesake, a single chandelier cell reaches out ...
Jun 18, 2020
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An early age of pregnancy (25 years and younger) is known to reduce the overall risk of breast cancer by over 30%. CSHL Assistant Professor Camila dos Santos spent several years teasing out the molecular details behind the ...
May 27, 2020
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Pancreatic ductal adenocarcinoma (PDA) is a deadly cancer, killing patients within a year. CSHL Professor Christopher Vakoc and his former postdoc Timothy Somerville discovered how pancreatic cells lose their identity, acquire ...
May 19, 2020
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In the urgent battle to treat COVID-19 patients, a group of eleven international medical research organizations is investigating whether overactive immune cells that produce neutrophil extracellular traps (NETs) cause the ...
Apr 16, 2020
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Cancer cells are notorious for their genetic disarray. A tumor cell can contain an abundance of DNA mutations and most have the wrong number of chromosomes. A missing or extra copy of a single chromosome creates an imbalance ...
Feb 24, 2020
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A genetic mutation that disrupts how DNA sends messages to the rest of a cell has been linked to a large number of blood cancers. Thanks to a collaboration between biologists at Cold Spring Harbor Laboratory (CSHL) and an ...
Jan 31, 2020
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