Cold Spring Harbor Laboratory

Genetics

Genome analysis just got personal

Life on Earth comes in a beautiful assortment of different shapes, sizes and colors, thanks to genetic mutations. Some mutations are beneficial, some are perilous, and some don't do much of anything. Every person has around ...

Medical research

Stopping a rare childhood cancer in its tracks

Scientists at Cold Spring Harbor Laboratory (CSHL) have discovered a new drug target for Ewing sarcoma, a rare kind of cancer usually diagnosed in children and young adults. Their experiments show that the cells causing this ...

Oncology & Cancer

Researchers develop new software for unlocking cancer's ancestry

Could knowing where your ancestors came from be the key to better cancer treatments? Maybe, but where would that key fit? How can we trace cancer's ancestral roots to modern-day solutions? For Cold Spring Harbor Laboratory ...

Oncology & Cancer

Cracking the mystery behind a deadly brain cancer

The brain cancer, glioblastoma, is a fierce and formidable opponent. Its millions of victims include Senator John McCain, President Biden's son, Beau, and famed film critic Gene Siskel, to name just a few. Most patients succumb ...

Neuroscience

Mapping the path from smell to perception

Our sense of smell has a powerful effect on our behavior and emotions. Aromas can evoke vivid memories of the past or warn us of a smoldering fire. Yet to neuroscientists, smell remains the most mysterious of our five senses.

Neuroscience

Got junk food on the brain? These cells may be to blame

A region of the brain called the amygdala is responsible for powerful emotions like fear. Now, researchers have found the amygdala may also be to blame for overeating. Cold Spring Harbor Laboratory (CSHL) Professor Bo Li ...

Neuroscience

Sniffing out the brain's smelling power

Since their discovery over 100 years ago, neurons called tufted cells, in the brain's olfactory bulb, have been difficult to study. The close proximity between tufted cells and other neurons called mitral cells has restricted ...

Medical research

The unexpected cells helping to shape young brains

When the brain first wires itself up in early development, it creates more connections than it actually needs. Some of these connections, or synapses, will transmit critical signals as young animals begin to sense their surroundings. ...

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