Cold Spring Harbor Laboratory

Neuroscience

New tool for investigating brain cells, Parkinson's, and more

NMDARs (N-methyl-D-aspartate receptors) serve as valves on nerve cells, controlling the flow of electrical signals in the brain. This special group of receptors is suspect in many neurological diseases, including Alzheimer's, ...

Oncology & Cancer

Vitamin B6, leukemia's deadly addiction

Scientists have discovered that Acute Myeloid Leukemia (AML) grows by taking advantage of the B6 vitamin to accelerate cell division. The research team from Cold Spring Harbor Laboratory (CSHL) and Memorial Sloan Kettering ...

Neuroscience

Abnormal neuron activity manifests as parental neglect

The brain undergoes dramatic change during the first years of life. Its circuits readily rewire as an infant and then child encounters new sights and sounds, taking in the world and learning to understand it. As the child ...

Neuroscience

How the brain balances pleasure and pain

As our brains take in information about the world and use it to steer our actions, two key principles guide our choices: seek pleasure and avoid pain. Researchers at Cold Spring Harbor Laboratory (CSHL) have zeroed in on ...

Oncology & Cancer

Milestone reached in new leukemia drug

Cold Spring Harbor Laboratory scientists, with chemists and cancer biologists from Dana-Farber Cancer Institute (DFCI), have developed a new therapy that extended the survival of mice with acute myeloid leukemia.

Neuroscience

The difference between an expert's brain and a novice's

When mice learn to do a new task, their brain activities change over time as they advance from 'novice' to 'expert.' The changes are reflected in the wiring of cell circuits and activities of neurons.

Neuroscience

BARseq builds a better brain map

Cold Spring Harbor Laboratory Professor Anthony Zador has taken the next step in his quest to solve exactly how the brain is wired.

Neuroscience

New brain research could change how concussions are treated

Traumatic brain injuries (TBI), including concussions, can be caused by anything from sports injuries to battlefield trauma. And they can have fatal or lasting effects. The results of a severe concussion—problems with thinking, ...

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