Cold Spring Harbor Laboratory
New automated imaging to greatly speed whole-brain mapping efforts
A new technology developed by neuroscientists at Cold Spring Harbor Laboratory (CSHL) transforms the way highly detailed anatomical images can be made of whole brains. Until now, means of obtaining such images ...
Medical research
Jan 15, 2012 |
4.3 / 5 (14) |
3
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ENCODE project: In massive genome analysis new data suggests 'gene' redefinition
Most people understand genes to be specific segments of DNA that determine traits or diseases that are inherited. Textbooks suggest that genes are copied ("transcribed") into RNA molecules, which are then used as templates ...
Genetics
Sep 05, 2012 |
5 / 5 (8) |
3
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New evidence for genetic basis of autism found
Scientists at Cold Spring Harbor Laboratory (CSHL) have discovered that one of the most common genetic alterations in autism -- deletion of a 27-gene cluster on chromosome 16 -- causes autism-like features. ...
Genetics
Oct 03, 2011 |
4.3 / 5 (9) |
6
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Team finds mechanism of one of the most powerful tumor-suppressor proteins, Chd5
A team of cancer researchers at Cold Spring Harbor Laboratory (CSHL) has solved the mystery of how one of the most powerful of the body's natural tumor-suppressing proteins, called Chd5, exerts its beneficial effects.
Cancer
Jan 10, 2013 |
4.5 / 5 (6) |
0
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Possible link between bacterium, colon cancer found
For the first time, a specific microorganism has been found to be associated with human colorectal cancer. In two studies published online today in Genome Research, independent research teams have identified Fusobacterium in col ...
Cancer
Oct 17, 2011 |
5 / 5 (5) |
0
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Neuroscientists propose revolutionary DNA-based approach to map wiring of whole brain
A team of neuroscientists has proposed a new and potentially revolutionary way of obtaining a neuronal connectivity map (the "connectome") of the whole brain of the mouse. The details are set forth in an essay published October ...
Neuroscience
Oct 23, 2012 |
5 / 5 (5) |
1
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Nobel laureate publishes novel hypothesis on curing late-stage cancers
In a new paper he regards "among my most important work since the double helix," Nobelist James Watson sets forth a novel hypothesis regarding the role of oxidants and antioxidants in cancers that are currently incurable, ...
Cancer
Jan 08, 2013 |
5 / 5 (4) |
0
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Scientists reverse Alzheimer's-like memory loss in animal models by blocking EGFR signaling
A team of neuroscientists and chemists from the U.S. and China today publish research suggesting that a class of currently used anti-cancer drugs as well as several previously untested synthetic compounds show effectiveness ...
Alzheimer's disease & dementia
Sep 24, 2012 |
4.8 / 5 (4) |
0
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Differences between human twins at birth highlight importance of intrauterine environment
Your genes determine much about you, but environment can have a strong influence on your genes even before birth, with consequences that can last a lifetime. In a study published online in Genome Research, researchers have f ...
Genetics
Jul 15, 2012 |
4.5 / 5 (4) |
9
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Team perfects non-lethal way of switching off essential genes in mice
One way of discovering a gene's function is to switch it off and observe how the loss of its activity affects an organism. If a gene is essential for survival, however, then switching it off permanently will ...
Genetics
Apr 14, 2011 |
5 / 5 (3) |
5
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Study solves birth and migration mysteries of cortex's powerful inhibitors, 'chandelier' cells
A team at CSHL for the 1st time reveals the birth timing and embryonic origin of a critical class of inhibitory brain cells called chandelier cells, tracing the specific paths they take during early development into the cerebral ...
Neuroscience
Nov 22, 2012 |
5 / 5 (3) |
2
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Neuroscientists show 'jumping genes' may contribute to aging-related brain defects
As the body ages, the physical effects are notable; wrinkles in the skin appear, physical exertion becomes harder. But there are also less visible processes going on. Inside aging brains there is another phenomenon at work, ...
Neuroscience
Apr 08, 2013 |
5 / 5 (3) |
0
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X-linked mental retardation protein is found to mediate synaptic plasticity in hippocampus
Scientists at Cold Spring Harbor Laboratory (CSHL) have solved part of a puzzle concerning the relationship between changes in the strength of synapses – the tiny gaps across which nerve cells in the brain communicate ...
Neuroscience
Oct 19, 2011 |
4.7 / 5 (3) |
1
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Cutting-edge imaging techniques for neuroscientists available in latest laboratory manual
Neuroscientists have long pioneered the use of new visualization techniques. Imaging in Neuroscience: A Laboratory Manual continues that tradition by presenting an outstanding collection of methods for vi ...
Neuroscience
Jul 20, 2011 |
5 / 5 (2) |
0
Powerful antibody-based strategy suggests a new therapeutic approach to diabetes and obesity
The work of a team of scientists at Cold Spring Harbor Laboratory (CSHL) led by Professor Nicholas Tonks FRS, suggests a way to overcome one of the major technical obstacles preventing a leading therapeutic target for diabetes ...
Medical research
Sep 29, 2011 |
5 / 5 (2) |
0
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