Cold Spring Harbor Laboratory

Oncology & Cancer

Cracking the mystery behind a deadly brain cancer

The brain cancer, glioblastoma, is a fierce and formidable opponent. Its millions of victims include Senator John McCain, President Biden's son, Beau, and famed film critic Gene Siskel, to name just a few. Most patients succumb ...

Oncology & Cancer

Massive genome havoc in breast cancer is revealed

In cancer cells, genetic errors wreak havoc. Misspelled genes, as well as structural variations—larger-scale rearrangements of DNA that can encompass large chunks of chromosomes—disturb carefully balanced mechanisms that ...

Neuroscience

The difference between an expert's brain and a novice's

When mice learn to do a new task, their brain activities change over time as they advance from 'novice' to 'expert.' The changes are reflected in the wiring of cell circuits and activities of neurons.

Oncology & Cancer

Possible link between bacterium, colon cancer found

For the first time, a specific microorganism has been found to be associated with human colorectal cancer. In two studies published online today in Genome Research, independent research teams have identified Fusobacterium ...

Medical research

The prostate cancer cell that got away

Cold Spring Harbor Laboratory (CSHL) Associate Professor Pavel Osten and Professor Lloyd Trotman have developed a new way to study the life history of prostate cancer in mice. The pair combined their expertise in whole-organ ...

Diseases, Conditions, Syndromes

Drug halts immune reactions to save damaged lungs

A team of scientists led by Cold Spring Harbor Laboratory (CSHL) have discovered that disulfiram, an FDA-approved drug, prevents the immune system from producing toxic webs known as neutrophil extracellular traps (NETs). ...

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