Cold Spring Harbor Laboratory

Genetics

A shift in the code: New method reveals hidden genetic landscape

With three billion letters in the human genome, it seems hard to believe that adding a DNA base here or removing a DNA base there could have much of an effect on our health. In fact, such insertions and deletions can dramatically ...

Oncology & Cancer

A way to prevent pancreatic cancer from spreading post-surgery?

Scientists at Cold Spring Harbor Laboratory (CSHL) have solved a mystery about how pancreatic cancer spreads following surgery in patients whose tumor is successfully removed. After surgery, patients' typically experience ...

Neuroscience

Neuroscientists pinpoint location of fear memory in amygdala

A rustle of undergrowth in the outback: it's a sound that might make an animal or person stop sharply and be still, in the anticipation of a predator. That "freezing" is part of the fear response, a reaction to a stimulus ...

Oncology & Cancer

Cancer cell's 'self eating' tactic may be its weakness

Cancer cells use a bizarre strategy to reproduce in a tumor's low-energy environment; they mutilate their own mitochondria! Researchers at Cold Spring Harbor Laboratory (CSHL) also know how this occurs, offering a promising ...

Oncology & Cancer

Researchers discover a new type of lung cancer

Researchers have discovered a new kind of small-cell lung cancer (SCLC). The discovery paves the way for developing personalized medicine approaches to target this previously unnoticed form of the disease.

Neuroscience

Scientists discover a new pathway for fear deep within the brain

Fear is primal. In the wild, it serves as a protective mechanism, allowing animals to avoid predators or other perceived threats. For humans, fear is much more complex. A normal amount keeps us safe from danger. But in extreme ...

Neuroscience

New brain research could change how concussions are treated

Traumatic brain injuries (TBI), including concussions, can be caused by anything from sports injuries to battlefield trauma. And they can have fatal or lasting effects. The results of a severe concussion—problems with thinking, ...

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