Cancer immunotherapies, which empower patients' immune systems to eliminate tumors, are revolutionizing cancer treatment. Many patients respond well to these treatments, sometimes experiencing long-lasting remissions. But ...
Oct 30, 2020
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Cold Spring Harbor Laboratory (CSHL) scientists have discovered neurons in the mouse brain that help an animal learn to avoid negative experiences. The cells reside in a part of the brain involved in regulating the motivations ...
Sep 15, 2020
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Immune cells play an unexpected role in fine-tuning the brain's neural circuits, according to research published in September, 2020 in Neuron. The immune cells that reside there, known as microglia, not only protect the brain ...
Sep 14, 2020
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138
Scientists at Cold Spring Harbor Laboratory (CSHL) and Stanford University have pinpointed the circuit in the brain that is responsible for sleepless nights in times of stress—and it turns out that circuit does more than ...
Sep 9, 2020
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Researchers have investigated the function of a complex mesh of muscle fibers that line the inner surface of the heart. The study, published in the journal Nature, sheds light on questions asked by Leonardo da Vinci 500 years ...
Aug 19, 2020
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A new method developed at Cold Spring Harbor Laboratory (CSHL) uses DNA sequencing to efficiently map long-range connections between different regions of the brain. The approach dramatically reduces the cost of mapping brain-wide ...
Jul 14, 2020
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204
Scientists at Cold Spring Harbor Laboratory (CSHL) have found that they can stop the growth of pancreatic cancer cells by interfering with the way the cells store cholesterol. Their findings in mice and lab-grown pancreas ...
Jul 7, 2020
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266
Within the intricate network of cells that make up the brain, chandelier cells stand out for their elaborate, branching structure. With an elegant shape similar to that of its namesake, a single chandelier cell reaches out ...
Jun 18, 2020
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107
Pancreatic ductal adenocarcinoma (PDA) is a deadly cancer, killing patients within a year. CSHL Professor Christopher Vakoc and his former postdoc Timothy Somerville discovered how pancreatic cells lose their identity, acquire ...
May 19, 2020
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472
Cancer cells are notorious for their genetic disarray. A tumor cell can contain an abundance of DNA mutations and most have the wrong number of chromosomes. A missing or extra copy of a single chromosome creates an imbalance ...
Feb 24, 2020
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