Columbia University Medical Center

Neuroscience

Yin and yang of serotonin neurons in mood regulation

Low levels of serotonin in the brain are known to play a role in depression and anxiety, and it is customary to treat these disorders with medications that increase the amount of this neurotransmitter. However, a new study ...

Dentistry

Genetic signature reveals new way to classify gum disease

Researchers at Columbia University Medical Center (CUMC) have devised a new system for classifying periodontal disease based on the genetic signature of affected tissue, rather than on clinical signs and symptoms. The new ...

Oncology & Cancer

New way to identify brain tumor aggressiveness

A comprehensive analysis of the molecular characteristics of gliomas—the most common malignant brain tumor—explains why some patients diagnosed with slow-growing (low-grade) tumors quickly succumb to the disease while ...

Oncology & Cancer

Pancreatic cancer accelerated by stress, finds study

A new study shows that stress accelerates the development of pancreatic cancer by triggering the release of "fight-or-flight" hormones. Beta-blockers—commonly used medications that inhibit these hormones—were found to ...

Medical research

Bone hormone influences brain development and cognition

Researchers from Columbia University Medical Center (CUMC) have found that the skeleton, acting through the bone-derived hormone osteocalcin, exerts a powerful influence on prenatal brain development and cognitive functions ...

Alzheimer's disease & dementia

In Alzheimer's, excess tau protein damages brain's GPS

Columbia University Medical Center (CUMC) researchers have discovered that the spatial disorientation that leads to wandering in many Alzheimer's disease patients is caused by the accumulation of tau protein in navigational ...

Dentistry

Dentists can identify people with undiagnosed diabetes

In a study, Identification of unrecognized diabetes and pre-diabetes in a dental setting, published in the July 2011 issue of the Journal of Dental Research, researchers at Columbia University College of Dental Medicine found ...

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