Columbia University Medical Center
Hundreds of alterations and potential drug targets to starve cancer tumors identified
A massive study analyzing gene expression data from 22 tumor types has identified multiple metabolic expression changes associated with cancer. The analysis, conducted by researchers at Columbia University Medical Center, ...
Cancer
Apr 21, 2013 |
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Portion of hippocampus found to play role in modulating anxiety
Columbia University Medical Center (CUMC) researchers have found the first evidence that selective activation of the dentate gyrus, a portion of the hippocampus, can reduce anxiety without affecting learning. ...
Neuroscience
Mar 06, 2013 |
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Schizophrenia genetic networks identified: Connection to autism found
Although schizophrenia is highly genetic in origin, the genes involved in the disorder have been difficult to identify. In the past few years, researchers have implicated several genes, but it is unclear how they act to produce ...
Neuroscience
Nov 11, 2012 |
4.3 / 5 (8) |
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Researchers identify dozens of new de novo genetic mutations in schizophrenia
Columbia University Medical Center (CUMC) researchers have identified dozens of new spontaneous genetic mutations that play a significant role in the development of schizophrenia, adding to the growing list of genetic variants ...
Genetics
Oct 03, 2012 |
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Stem cells improve visual function in blind mice
An experimental treatment for blindness, developed from a patient's skin cells, improved the vision of blind mice in a study conducted by Columbia ophthalmologists and stem cell researchers.
Medical research
Oct 01, 2012 |
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Study pinpoints a genetic cause of most lethal brain tumor, may lead to new treatment
Researchers at Columbia University Medical Center (CUMC) have discovered that some cases of glioblastoma, the most common and aggressive form of primary brain cancer, are caused by the fusion of two adjacent ...
Cancer
Jul 26, 2012 |
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Computational tool translates complex data into simplified 2-dimensional images
In their quest to learn more about the variability of cells between and within tissues, biomedical scientists have devised tools capable of simultaneously measuring dozens of characteristics of individual ...
Medical research
May 19, 2013 |
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Type 1 diabetes and heart disease linked by inflammatory protein
Type 1 (insulin-dependent) diabetes appears to increase the risk of heart disease, the leading cause of death among people with high blood sugar, partly by stimulating the production of calprotectin, a protein that sparks ...
Inflammatory disorders
May 07, 2013 |
4.5 / 5 (2) |
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High levels of glutamate in brain may kick-start schizophrenia
An excess of the brain neurotransmitter glutamate may cause a transition to psychosis in people who are at risk for schizophrenia, reports a study from investigators at Columbia University Medical Center (CUMC) published ...
Neuroscience
Apr 18, 2013 |
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ABCA7 gene associated with almost doubled Alzheimer's risk in African-Americans
African-Americans with a variant of the ABCA7 gene have almost double the risk of developing late-onset Alzheimer's disease compared with African-Americans who lack the variant. The largest genome-wide search for Alzheimer's ...
Genetics
Apr 09, 2013 |
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Omega-3 lipid emulsions markedly protect brain after stroke in mouse study
Triglyceride lipid emulsions rich in an omega-3 fatty acid injected within a few hours of an ischemic stroke can decrease the amount of damaged brain tissue by 50 percent or more in mice, reports a new study by researchers ...
Neuroscience
Feb 20, 2013 |
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Scientists discover how animals taste, and avoid, high salt concentrations
Researchers have discovered how the tongue detects high concentrations of salt, the first step in a salt-avoiding behavior common to most mammals. The findings could serve as a springboard for the development of taste modulators ...
Health
Feb 13, 2013 |
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Study points to possible cause of, and treatment for, non-familial Parkinson's
Columbia University Medical Center (CUMC) researchers have identified a protein trafficking defect within brain cells that may underlie common non-familial forms of Parkinson's disease. The defect is at a point of convergence ...
Parkinson's & Movement disorders
Feb 06, 2013 |
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New research may explain why obese people have higher rates of asthma
A new study led by Columbia University Medical Center (CUMC) researchers has found that leptin, a hormone that plays a key role in energy metabolism, fertility, and bone mass, also regulates airway diameter. The findings ...
Medical research
Jan 08, 2013 |
5 / 5 (1) |
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New insights into how immune system fights atherosclerosis
A study led by Columbia University Medical Center (CUMC) researchers has found that an important branch of the immune system, in reaction to the development of atherosclerotic lesions, mounts a surprisingly robust anti-inflammatory ...
Immunology
Dec 21, 2012 |
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