In a study involving thousands of participants, a new blood test detected more than 50 types of cancer as well as their location within the body with a high degree of accuracy, according to an international team of researchers ...
Mar 30, 2020
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804
In patients with advanced ovarian cancer, a combination of drugs known as immune checkpoint inhibitors and PARP inhibitors can produce powerful remissions, clinical trials have shown, but up until now investigators haven't ...
Mar 19, 2020
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53
Deep within the lining of the human intestine lies the source of the organ's ability to renew itself and recover from damage: intestinal stem cells (ISCs), lodged in pockets of tissue called crypts, generate the cells that ...
Feb 20, 2020
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326
A metabolic imbalance in some cancer patients following treatment with a checkpoint inhibitor drug, nivolumab, is associated with resistance to the immunotherapy agent and shorter survival, report scientists from Dana-Farber ...
Sep 25, 2019
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41
Scientists studying a highly cancer-prone family have identified a rare, inherited gene mutation that dramatically raises the lifetime risk of pancreatic and other cancers.
Aug 12, 2019
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363
Researchers have discovered two distinct subtypes of pancreatic neuroendocrine tumors—known as pNETs—that have dramatically different risks of recurrence following surgical treatment [or surgery]. The finding could yield ...
Jul 2, 2019
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3
In patients with chronic lymphocytic leukemia (CLL), the rate of disease growth is apt to follow one of three trajectories: relentlessly upward, steadily level, or something in between, scientists at Dana-Farber Cancer Institute, ...
May 29, 2019
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28
Cancer cells adapt to potentially fatal mutations and other molecular malfunctions by adjusting one or more other genes' activity, in the process becoming dependent on those genes for their survival and growth. The resulting ...
Apr 11, 2019
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100
A combination of two drugs—one of them an immunotherapy agent—could become a new standard, first-line treatment for patients with metastatic kidney cancer, says an investigator from Dana-Farber Cancer Institute, reporting ...
Feb 17, 2019
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62
Scientists have discovered a previously unknown molecular vulnerability in two rare, aggressive, and hard-to-treat types of cancer, and say it may be possible to attack this weakness with targeted drugs.
Nov 5, 2018
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93
