Friedrich Miescher Institute for Biomedical Research

The Friedrich Miescher Institute for Biomedical Research (FMI) is part of the Novartis Research Foundation and is a world-class center for basic research in life sciences based in Basel, Switzerland. The FMI is devoted to the pursuit of fundamental biomedical research. Areas of expertise are: In these fields the FMI has gained international recognition as a center of excellence in innovative biomedical research. Research is carried out in 22 independent but highly interactive research teams. In addition, seven technology platforms, ranging from functional genomics to microscopy and imaging, support the research activities with cutting-edge technology. As of 2011, the institute counts 320 collaborators of which 90 are postgraduate students participating in the FMI International PhD Program, 100 are postdoctoral collaborators and 22 are research group leaders. Since 2004, the institute is led by Susan M. Gasser. in chronological order The FMI is an affiliated institute of the University of Basel. It provides biomedical research and career training for over 90 PhD students. FMI selects its highly international student body during a twice-yearly interview-based selection program.

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Controlling cell-fate decisions

Rafal Ciosk and his group at the FMI have identified an important link between the Notch signaling pathway and PRC2-mediated gene silencing. They showed that a fine balance between epigenetic silencing and signaling is crucial ...

Sep 23, 2016
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What you see is not always what you get

Georg Keller and his group at the Friedrich Miescher Institute for Biomedical Research (FMI) have identified neurons in the visual cortex whose activity predicts an upcoming visual stimulus. This activity emerges with experience ...

Sep 19, 2016
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Aggressiveness of acute myeloid leukemia elucidated

Antoine Peters and colleagues at the Basel University Children's Hospital (UKBB) have discovered why acute leukemias with the same genetic abnormality vary in their aggressiveness based on their cellular origin. They found ...

Jun 24, 2016
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How fear makes us freeze

Andreas Lüthi and his group at the Friedrich Miescher Institute for Biomedical Research (FMI) have identified and characterized the neuronal circuitry in the brain, which controls defensive behavior in threatening situations. ...

Jun 01, 2016
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Unraveling complex neuronal networks

One of the fundamental questions in neuroscience is how neuronal circuits are wired to process information. The research group led by Rainer Friedrich has developed new methods to determine the complex morphology of densely ...

May 02, 2016
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Targeting cancer proteins for degradation

Cancer research is increasingly focusing on therapeutic approaches in which disease causing proteins are marked for early degradation. Nicolas Thomä and his group at the Friedrich Miescher Institute for Biomedical Research ...

Feb 24, 2016
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Mapping face sensation in the brainstem

Filippo Rijli and his group at the FMI have shown how the formation of a sensory topographic map in the brainstem is controlled by a single transcription factor, thus shedding light on a decades-old question in neuroscience. ...

Oct 23, 2015
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Controlling anxiety

Researchers at Andreas Lüthi's laboratory have identified a cell type in the brain, which controls anxiety - a complex behavioral state - and have elucidated the underlying mechanisms. These findings thus improve our understanding ...

Sep 23, 2015
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