Friedrich Miescher Institute for Biomedical Research

The Friedrich Miescher Institute for Biomedical Research (FMI) is part of the Novartis Research Foundation and is a world-class center for basic research in life sciences based in Basel, Switzerland. The FMI is devoted to the pursuit of fundamental biomedical research. Areas of expertise are: In these fields the FMI has gained international recognition as a center of excellence in innovative biomedical research. Research is carried out in 22 independent but highly interactive research teams. In addition, seven technology platforms, ranging from functional genomics to microscopy and imaging, support the research activities with cutting-edge technology. As of 2011, the institute counts 320 collaborators of which 90 are postgraduate students participating in the FMI International PhD Program, 100 are postdoctoral collaborators and 22 are research group leaders. Since 2004, the institute is led by Susan M. Gasser. in chronological order The FMI is an affiliated institute of the University of Basel. It provides biomedical research and career training for over 90 PhD students. FMI selects its highly international student body during a twice-yearly interview-based selection program.

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Mapping face sensation in the brainstem

Filippo Rijli and his group at the FMI have shown how the formation of a sensory topographic map in the brainstem is controlled by a single transcription factor, thus shedding light on a decades-old question in neuroscience. ...

Oct 23, 2015
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Controlling anxiety

Researchers at Andreas Lüthi's laboratory have identified a cell type in the brain, which controls anxiety - a complex behavioral state - and have elucidated the underlying mechanisms. These findings thus improve our understanding ...

Sep 23, 2015
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Genetic guides to epigenetics

Dirk Schübeler and his group at the Friedrich Miescher Institute for Biomedical Research (FMI) identify determinants that set epigenetic marks along the genome. The new study, published in Nature, shows that genetic activity ...

Feb 10, 2015
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Giant proteins determine properties of neurons

Giant membrane-associated proteins called ankyrins extend into the cytoplasm to arrange and stabilize microtubules in axons and synapses. This determines not only the diameter and hence the functional properties of axons, ...

Apr 14, 2015
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New function for rods in daylight

(Medical Xpress)—Vision – so crucial to human health and well-being – depends on job-sharing by just a few cell types, the rod cells and cone cells, in our retina. Botond Roska and his group have identified a novel ...

Nov 19, 2014
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Mechanism of action of thalidomide elucidated

(Medical Xpress)—Scientists led by Nicolas Thomä at the Friedrich Miescher Institute for Biomedical Research have clarified the workings of thalidomide at the molecular level. Their analysis of various structures, published ...

Jul 17, 2014
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Inducing visual function

Scientists from the groups of Botond Roska and Witold Filipowicz at the Friedrich Miescher Institute for Biomedical Research have resolved the mechanism controlling the maintenance of the light sensitive "antennas" of photoreceptors ...

Jul 02, 2014
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Releasing the neuronal brakes for learning

(Medical Xpress)—Learning can only occur if certain neuronal "brakes" are released. As the group led by Andreas Lüthi at the Friedrich Miescher Institute for Biomedical Research has now discovered, learning processes in ...

May 22, 2014
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