Gladstone Institutes

Alzheimer's disease & dementia

New study reveals how blood triggers brain disease

In patients with neurological diseases like Alzheimer's disease and multiple sclerosis, immune cells in the brain known as microglia that normally fulfill beneficial functions become harmful to neurons, leading to cognitive ...

Endocrinology & Metabolism

How high altitude changes your body's metabolism

Compared to those of us who live at sea level, the 2 million people worldwide who live above 4,500 meters (or 14,764 feet) of elevation—about the height of Mount Rainier, Mount Whitney, and many Colorado and Alaska peaks—have ...

Medical research

New antiviral therapy may block COVID-19 transmission

By the time you test positive for COVID-19, the SARS-CoV-2 virus has already taken up residence in your respiratory system. With each breath, you expel invisible viral particles into the air—a process known as viral shedding. ...

Medical research

Pathway deep in the brain makes it resilient after injury

For days, and even years, after someone suffers a stroke or traumatic brain injury, they have an increased risk of developing epilepsy. Now, researchers at Gladstone Institutes discovered that star-shaped cells called astrocytes ...

Oncology & Cancer

Scientists prevent 'exhaustion' in cancer-fighting T cells

When faced with a formidable foe for months on end, the immune system's T cells begin to tire. Whether fighting a cancer or a chronic infection, they become less effective over time, a phenomenon dubbed "T cell exhaustion" ...

Immunology

'Natural immunity' from omicron is weak and limited, study finds

In unvaccinated people, infection with the omicron variant of SARS-CoV-2 provides little long-term immunity against other variants, according to a new study by researchers at Gladstone Institutes and UC San Francisco (UCSF), ...

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