H. Lee Moffitt Cancer Center & Research Institute

Researchers analyze how Spanish smoking relapse booklets are distributed

Researchers from Moffitt Cancer Center and the University of South Florida have evaluated how Florida health care and social service agencies distribute "Libres para Siempre", a Spanish smoking relapse prevention booklet ...

Addiction created May 17, 2013 | popularity not rated yet | comments 0

Cancer biorepository speeds clinical trials, drug development, analysis shows

Researchers at Moffitt Cancer Center say identifying and selecting participants for phase II cancer clinical trials from a centralized warehouse of patient-donated biological data expedites participant accrual, reduces trial ...

Cancer created May 08, 2013 | popularity not rated yet | comments 0

Moffitt researchers identify unique immune gene signature across thousands of patients' solid tumors

(Medical Xpress)—Researchers at Moffitt Cancer Center have discovered a unique immune gene signature that can predict the presence of microscopic lymph node-like structures in metastatic melanoma. The presence of these ...

Genetics created Oct 25, 2012 | popularity 4.5 / 5 (2) | comments 0 | with audio podcast

Researchers say silencing of retinoblastoma gene regulates differentiation of myeloid cells

Researchers at the Moffitt Cancer Center have found a potential mechanism by which immune suppressive myeloid-derived suppressor cells can prevent immune response from developing in cancer. This mechanism includes silencing ...

Immunology created Feb 19, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Researchers and colleagues identify PHF20, a regulator of gene P53

Researchers at Moffitt Cancer Center and colleagues have identified PHF20, a novel transcriptional factor, and clarified its role in maintaining the stability and transcription of p53, a gene that allows for both normal cell ...

Cancer created Aug 24, 2012 | popularity not rated yet | comments 0 | with audio podcast

Deficiency in p53 anti-tumor protein delays DNA repair after radiation

Researchers at Moffitt Cancer Center have found that a deficiency in an important anti-tumor protein, p53, can slow or delay DNA repair after radiation treatment. They suggest that this is because p53 regulates the expression ...

Cancer created Apr 23, 2013 | popularity 4 / 5 (1) | comments 0 | with audio podcast

Researchers find genetic predictors of fatigue for some prostate cancer patients

Researchers at Moffitt Cancer Center and the University of South Florida have found that men with prostate cancer who receive androgen deprivation therapy may predictably suffer from fatigue if they have single nucleotide ...

Cancer created Oct 26, 2012 | popularity not rated yet | comments 0 | with audio podcast

Researchers design small molecule to disrupt cancer-causing protein

Researchers at Moffitt Cancer Center and colleagues at the University of South Florida have developed a small molecule that inhibits STAT3, a protein that causes cancer. This development could impact the treatment of several ...

Cancer created Mar 26, 2013 | popularity 4.5 / 5 (2) | comments 0 | with audio podcast

Researchers find novel predictor for MDS progression risk

Researchers at Moffitt Cancer Center and colleagues have discovered that changes in the physical characteristics of the effector memory regulatory T cell can predict the progression risk of myelodysplastic syndromes (MDS) ...

Immunology created Sep 13, 2012 | popularity not rated yet | comments 0 | with audio podcast

Race, ethnicity affect likelihood of finding suitable unrelated stem cell donor for cancer patients

(Medical Xpress)—Researchers at Moffitt Cancer Center and colleagues have published a study describing the greater difficulty in finding matched, unrelated donors for non-Caucasian patients who are candidates for hematopoietic ...

Cancer created Sep 11, 2012 | popularity not rated yet | comments 0 | with audio podcast

Tumor cells engineer acidity to drive cell invasion

Researchers at Moffitt Cancer Center and colleagues at Wayne State University School of Medicine investigated the acidity in solid tumors to determine if pH levels play a role in cancer cell invasion in surrounding tissues. ...

Cancer created Jan 25, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Researchers find potential new therapeutic target for treating non-small cell lung cancer

Researchers at Moffitt Cancer Center have found a potential targeted therapy for patients with tobacco-associated non-small cell lung cancer. It is based on the newly identified oncogene IKBKE, which helps regulate immune ...

Cancer created Feb 15, 2013 | popularity not rated yet | comments 0 | with audio podcast

Researchers develop automated breast density test linked to cancer risk

Researchers at Moffitt Cancer Center and colleagues at the Mayo Clinic in Rochester, Minn., have developed a novel computer algorithm to easily quantify a major risk factor for breast cancer based on analysis of a screening ...

Cancer created Feb 01, 2013 | popularity not rated yet | comments 0 | with audio podcast

Researchers find acidic pH microenvironments in tumors aid tumor cell survival

Researchers at Moffitt Cancer Center and colleagues at the University of South Florida and Wayne State University have discovered that tumor cell survival relies on adaptation to acidic conditions in the tumor microenvironment. ...

Cancer created Sep 06, 2012 | popularity not rated yet | comments 0 | with audio podcast

Researchers use mathematics to fight cancer

Using mathematical models, researchers in the Integrated Mathematical Oncology (IMO) program at Moffitt Cancer Center are focusing their research on the interaction between the tumor and its microenvironment and the "selective ...

Cancer created May 03, 2012 | popularity 4 / 5 (1) | comments 0 | with audio podcast