H. Lee Moffitt Cancer Center & Research Institute
Researchers analyze how Spanish smoking relapse booklets are distributed
Researchers from Moffitt Cancer Center and the University of South Florida have evaluated how Florida health care and social service agencies distribute "Libres para Siempre", a Spanish smoking relapse prevention booklet ...
Addiction
May 17, 2013 |
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Cancer biorepository speeds clinical trials, drug development, analysis shows
Researchers at Moffitt Cancer Center say identifying and selecting participants for phase II cancer clinical trials from a centralized warehouse of patient-donated biological data expedites participant accrual, reduces trial ...
Cancer
May 08, 2013 |
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Moffitt researchers identify unique immune gene signature across thousands of patients' solid tumors
(Medical Xpress)—Researchers at Moffitt Cancer Center have discovered a unique immune gene signature that can predict the presence of microscopic lymph node-like structures in metastatic melanoma. The presence of these ...
Genetics
Oct 25, 2012 |
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Researchers say silencing of retinoblastoma gene regulates differentiation of myeloid cells
Researchers at the Moffitt Cancer Center have found a potential mechanism by which immune suppressive myeloid-derived suppressor cells can prevent immune response from developing in cancer. This mechanism includes silencing ...
Immunology
Feb 19, 2013 |
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Researchers and colleagues identify PHF20, a regulator of gene P53
Researchers at Moffitt Cancer Center and colleagues have identified PHF20, a novel transcriptional factor, and clarified its role in maintaining the stability and transcription of p53, a gene that allows for both normal cell ...
Cancer
Aug 24, 2012 |
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Deficiency in p53 anti-tumor protein delays DNA repair after radiation
Researchers at Moffitt Cancer Center have found that a deficiency in an important anti-tumor protein, p53, can slow or delay DNA repair after radiation treatment. They suggest that this is because p53 regulates the expression ...
Cancer
Apr 23, 2013 |
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Researchers find genetic predictors of fatigue for some prostate cancer patients
Researchers at Moffitt Cancer Center and the University of South Florida have found that men with prostate cancer who receive androgen deprivation therapy may predictably suffer from fatigue if they have single nucleotide ...
Cancer
Oct 26, 2012 |
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Researchers design small molecule to disrupt cancer-causing protein
Researchers at Moffitt Cancer Center and colleagues at the University of South Florida have developed a small molecule that inhibits STAT3, a protein that causes cancer. This development could impact the treatment of several ...
Cancer
Mar 26, 2013 |
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Researchers find novel predictor for MDS progression risk
Researchers at Moffitt Cancer Center and colleagues have discovered that changes in the physical characteristics of the effector memory regulatory T cell can predict the progression risk of myelodysplastic syndromes (MDS) ...
Immunology
Sep 13, 2012 |
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Race, ethnicity affect likelihood of finding suitable unrelated stem cell donor for cancer patients
(Medical Xpress)—Researchers at Moffitt Cancer Center and colleagues have published a study describing the greater difficulty in finding matched, unrelated donors for non-Caucasian patients who are candidates for hematopoietic ...
Cancer
Sep 11, 2012 |
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Tumor cells engineer acidity to drive cell invasion
Researchers at Moffitt Cancer Center and colleagues at Wayne State University School of Medicine investigated the acidity in solid tumors to determine if pH levels play a role in cancer cell invasion in surrounding tissues. ...
Cancer
Jan 25, 2013 |
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Researchers find potential new therapeutic target for treating non-small cell lung cancer
Researchers at Moffitt Cancer Center have found a potential targeted therapy for patients with tobacco-associated non-small cell lung cancer. It is based on the newly identified oncogene IKBKE, which helps regulate immune ...
Cancer
Feb 15, 2013 |
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Researchers develop automated breast density test linked to cancer risk
Researchers at Moffitt Cancer Center and colleagues at the Mayo Clinic in Rochester, Minn., have developed a novel computer algorithm to easily quantify a major risk factor for breast cancer based on analysis of a screening ...
Cancer
Feb 01, 2013 |
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Researchers find acidic pH microenvironments in tumors aid tumor cell survival
Researchers at Moffitt Cancer Center and colleagues at the University of South Florida and Wayne State University have discovered that tumor cell survival relies on adaptation to acidic conditions in the tumor microenvironment. ...
Cancer
Sep 06, 2012 |
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Researchers use mathematics to fight cancer
Using mathematical models, researchers in the Integrated Mathematical Oncology (IMO) program at Moffitt Cancer Center are focusing their research on the interaction between the tumor and its microenvironment and the "selective ...
Cancer
May 03, 2012 |
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