Harvard Medical School

Comparing mouse and human immune systems: Few differences charted in map to translate mouse findings to humans

(Medical Xpress)—It is a familiar note struck when authors conclude their reports on experiments conducted in mouse models: They suggest caution when translating their findings from mouse to human. A variation ...

Medical research created Apr 02, 2013 | popularity 4 / 5 (1) | comments 0 | with audio podcast

Sizing up bone growth: A surprising cellular mechanism drives skeletal proportions

(Medical Xpress)—Stroll through the Harvard Museum of Natural History and gaze up at the whale skeleton looming overhead. Look down at the furry foxes curled up inside their glass display cases. Don't forget ...

Medical research created Mar 14, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

New study validates longevity pathway: Findings identify universal mechanism for activating anti-aging pathway

A new study demonstrates what researchers consider conclusive evidence that the red wine compound resveratrol directly activates a protein that promotes health and longevity in animal models. What's more, the researchers ...

Medical research created Mar 07, 2013 | popularity 4.8 / 5 (20) | comments 6 | with audio podcast

A treatment for ALS? Neural stem cell transplants slow progression of disease

(Medical Xpress)—Results from a meta-analysis of 11 independent amyotrophic lateral sclerosis research studies are giving hope to the ALS community by showing, for the first time, that the fatal disease ...

Neuroscience created Jan 03, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Structure of a bond formed by two proteins critical for hearing and balance described for the first time

Researchers have mapped the precise 3-D atomic structure of a thin protein filament critical for cells in the inner ear and calculated the force necessary to pull it apart.

Medical research created Nov 07, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Cancer may require simpler genetic mutations than previously thought

Chromosomal deletions in DNA often involve just one of two gene copies inherited from either parent. But scientists haven't known how a deletion in one gene from one parent, called a "hemizygous" deletion, can contribute ...

Cancer created May 25, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Researchers rebuild the brain's circuitry

Neuron transplants have repaired brain circuitry and substantially normalized function in mice with a brain disorder, an advance indicating that key areas of the mammalian brain are more reparable than was ...

Neuroscience created Nov 24, 2011 | popularity 4.6 / 5 (20) | comments 2 | with audio podcast

Bacterial genes tell the tale of an outbreak's evolution

Researchers at Harvard Medical School and Children's Hospital Boston have retraced the evolution of an unusual bacterial infection as it spread among cystic fibrosis patients by sequencing scores of samples collected during ...

Genetics created Nov 13, 2011 | popularity not rated yet | comments 0 | with audio podcast

New clue to Parkinson's: Shape of key protein surprises researchers

A new study finds that a protein key to Parkinson's disease has likely been mischaracterized. The protein, alpha-synuclein, appears to have a radically different structure in healthy cells than previously thought, challenging ...

Medical research created Aug 14, 2011 | popularity 4.8 / 5 (17) | comments 1 | with audio podcast

World's most advanced genetic map created

A consortium led by scientists at the University of Oxford and Harvard Medical School has constructed the world's most detailed genetic map.

Genetics created Jul 20, 2011 | popularity 5 / 5 (6) | comments 3 | with audio podcast

Population genetics reveals shared ancestries

More than just a tool for predicting health, modern genetics is upending long-held assumptions about who we are. A new study by Harvard researchers casts new light on the intermingling and migration of European, Middle Eastern ...

Genetics created May 24, 2011 | popularity 4.8 / 5 (10) | comments 15 | with audio podcast

Endothelium, heal thyself: A fresh look at this resilient, adaptable tissue

(Medical Xpress)—The endothelium, the cellular layer lining the body's blood vessels, is extremely resilient. Measuring just a few hundred nanometers in thickness, this super-tenuous structure routinely ...

Medical research created May 16, 2013 | popularity 4 / 5 (2) | comments 1 | with audio podcast

New cancer driver found: Monoclonal antibody therapy stops tumor growth in mice

(Medical Xpress)—Approximately 90 percent of cancers start within tissues that form the inner linings of various organs. Decades of accumulated genetic mutations can, on occasion, induce cells specialized ...

Cancer created May 08, 2013 | popularity 5 / 5 (7) | comments 0 | with audio podcast

After age 18, asthma care deteriorates

It is widely accepted that medical insurance helps older adults with chronic health problems to receive better care. But what about young adults between the ages of 18 and 25, a demographic that also tends to have the lowest ...

Pediatrics created Apr 22, 2013 | popularity not rated yet | comments 0 | with audio podcast

The gene therapy renaissance: How experimental technique overcame a troubled legacy and is now helping the blind to see

(Medical Xpress)—In 1999, researchers at the University of Pennsylvania injected 19 people with a virus carrying a gene designed to correct a rare metabolic disease. Early results appeared promising: Among ...

Genetics created Apr 19, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast