Helmholtz Association of German Research Centres
Researchers find controlling element of Huntington's disease
A three molecule complex may be a target for treating Huntington's disease, a genetic disorder affecting the brain. This finding by an international research team including scientists from the German Center for Neurodegenerative ...
Diseases, Conditions, Syndromes
Feb 26, 2013 |
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GI tract bacteria may protect against autoimmune disease
Early life exposure to normal bacteria of the GI tract (gut microbes) protects against autoimmune disease in mice, according to research published on-line in the January 17 edition of Science. The study ...
Immunology
Jan 17, 2013 |
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How individuality develops? Experience leads to the growth of new brain cells
How do organisms evolve into individuals that are distinguished from others by their own personal brain structure and behavior? Scientists in Dresden, Berlin, Münster, and Saarbrücken have now taken a decisive step towards ...
Neuroscience
May 09, 2013 |
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Metastasis stem cells in the blood of breast cancer patients discovered
Individual cancer cells that break away from the original tumor and circulate through the blood stream are considered responsible for the development of metastases. These dreaded secondary tumors are the ...
Cancer
Apr 22, 2013 |
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Transmission routes of spreading protein particles
In diseases like Alzheimer's and Parkinson's endogenous proteins accumulate in the brain, eventually leading to the death of nerve cells. These deposits, which consist of abnormally formed proteins, are supposed to migrate ...
Neuroscience
Mar 27, 2013 |
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New insights into the development of the heart
Viewed from the outside, our body looks completely symmetrical. However, most internal organs – including the heart – are formed asymmetrically. The right side of the heart is responsible for pulmonary circulation; the ...
Medical research
Mar 26, 2013 |
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Evolution in the antibody factory: How immune cells are able to advance their own evolution
Immune system B cells play a crucial role in the defence of pathogens; when they detect such an intruder, they produce antibodies that help to combat the enemy. They concurrently and continuously improve ...
Immunology
Mar 11, 2013 |
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'Healthier hormones' through diet and exercise
Weight loss—by dietary changes alone or combined with physical exercise—has a positive impact on the production of adipose tissue hormones: Adipose tissue produces less leptin but, instead, more adiponectin, which counteracts ...
Health
Mar 07, 2013 |
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Misplaced molecules: New insights into the causes of dementia
A team of German and Belgian researchers has succeeded in gaining new insights into the causes of certain movement disorders and forms of dementia. Scientists including Bettina Schmid and Christian Haass from the German Center ...
Neuroscience
Mar 01, 2013 |
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Translation error tracked in the brain of dementia patients
In certain dementias silent areas of the genetic code are translated into highly unusual proteins by mistake. An international team of scientists including researchers from the German Center for Neurodegenerative ...
Neuroscience
Feb 07, 2013 |
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Pair of proteins gets brain cells into shape
Scientists at the German Center for Neurodegenerative Diseases in Bonn have gained new insights into the early phase of the brain's development. In cooperation with researchers of the Max Planck Institute of Neurobiology, ...
Neuroscience
Dec 20, 2012 |
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Cocktail boosts immune cells in fighting cancer
Natural killer cells, as part of the body´s immune system, can effectively fight cancer. Unfortunately, they quickly lose their aggressiveness and hence are unable to reject solid tumors. Scientists from the German Cancer ...
Cancer
Dec 06, 2012 |
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Molecular knock-out alleviates Alzheimer's symptoms in mice
Researchers at the German Center for Neurodegenerative Diseases (DZNE) and the University Medical Center Göttingen (UMG) have identified an enzyme as a possible target for the treatment of Alzheimer's disease. The protein ...
Alzheimer's disease & dementia
Nov 30, 2012 |
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Feel-good hormone helps to jog the memory
The feel-good hormone dopamine improves long-term memory. This is the finding of a team lead by Emrah Düzel, neuroscientist at the German Center for Neurodegenerative Diseases and the University of Magdeburg. The researchers ...
Neuroscience
Nov 08, 2012 |
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Scientists find Achilles' heel of cancer cells
Several substances inhibiting so-called HDAC enzymes have been studied in trials searching for new anti-cancer drugs in recent years. "Trials have shown that HDAC inhibitors are very effective in arresting growth of cultured ...
Cancer
Nov 05, 2012 |
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