Institut National de la Sante et de la Recherche Medicale

Inflammatory disorders

A vaccine against chronic inflammatory diseases

In animals, a vaccine modifying the composition and function of the gut microbiota provides protection against the onset of chronic inflammatory bowel diseases and certain metabolic disorders, such as diabetes and obesity. ...

Cardiology

Is physical activity always good for the heart?

Physical activity is thought to be our greatest ally in the fight against cardiovascular disease. But there may be significant variations in its protective effects across a range of different situations, such as regularly ...

Oncology & Cancer

Pediatric cancers: Why some forms of leukemia only affect children

Acute myeloid leukemia (AML) mainly affects children, with often poor prognosis despite several decades of research into more effective treatments. A new study explains why some forms of leukemia develop in very young children ...

Neuroscience

Is the creativity of the human mind rooted in errors?

Why do some of our choices appear to be driven by a desire to explore the unknown? An Inserm team from École Normale Supérieure led by Valentin Wyart has shown that most of these choices are not motivated by curiosity, ...

Genetics

Rare diseases: Over 300 million patients affected worldwide

Rare diseases represent a global problem. Until now, the lack of data made it difficult to estimate their prevalence. Created and coordinated by Inserm, the Orphanet database contains the largest amount of epidemiological ...

Immunology

Atopic dermatitis: How allergens get on our nerves

Dry skin, pain, and itching... Atopic dermatitis affects the everyday lives of nearly 20% of children, and up to 5% of adults. The condition can have a significant impact on the quality of life of these patients.

Genetics

A protein essential for chikungunya virus replication identified

Originally from Africa, chikungunya is aptly named. It derives from a word in the Kimakonde language meaning "to become contorted," because the severe muscle and joint pains endured by the patients prevent them from moving ...

Obstetrics & gynaecology

High-risk pregnancy: The interferon effect

High-risk pregnancies occur frequently, and have multiple causes. It is estimated that 10 to 20 percent of pregnant women miscarry during their first trimester of pregnancy. Slow fetal growth may also arise as a result of ...

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