Institute for Quality and Efficiency in Health Care

Medications

Talimogene laherparepvec in melanoma: Added benefit not proven

Talimogene laherparepvec (trade name: Imlygic) has been approved since December 2015 for adults with advanced melanoma. The German Institute for Quality and Efficiency in Health Care (IQWiG) examined in a dossier assessment ...

Medications

Crizotinib in bronchial carcinoma: New data not informative

Crizotinib (trade name: Xalkori) has been available since 2012 for patients with advanced non-small cell lung cancer (bronchial carcinoma) with high activity of the enzyme anaplastic lymphoma kinase (ALK) who have already ...

Medications

Eribulin in liposarcoma: Added benefit not proven

Eribulin (trade name: Halaven) has been approved since May 2016 for the treatment of adults with advanced liposarcoma. The German Institute for Quality and Efficiency in Health Care (IQWiG) examined in a dossier assessment ...

Medications

Elotuzumab in multiple myeloma: Added benefit not proven

The monoclonal antibody elotuzumab has been approved in combination with lenalidomide and dexamethasone since May 2016 for further treatment of multiple myeloma in adults who have received at least one previous treatment. ...

Medications

Brivaracetam in epilepsy: Added benefit still not proven

Brivaracetam (trade name: Briviact) has been approved since January 2016 as add-on therapy for adults and adolescents from 16 years of age with epileptic seizures. The German Institute for Quality and Efficiency in Health ...

Medications

Ramucirumab in stomach cancer: Added benefit not proven

Ramucirumab (trade name: Cyramza) is a monoclonal antibody, which blocks a receptor, reducing the growth of blood vessels and so reducing blood supply to the tumours. This aims to slow the growth of the tumours. As a so-called ...

Medications

Ospemifene in vulvovaginal atrophy: Added benefit not proven

Ospemifene (tradename: Senshio) is approved for the treatment of moderate to severe symptomatic vulvovaginal atrophy (VVA) in post-menopausal women who are not candidates for local vaginal oestrogen therapy. The drug has ...

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