Johns Hopkins University School of Medicine

Enzyme-activating antibodies revealed as marker for most severe form of rheumatoid arthritis

In a series of lab experiments designed to unravel the workings of a key enzyme widely considered a possible trigger of rheumatoid arthritis, researchers at Johns Hopkins have found that in the most severe ...

Arthritis & Rheumatism created 13 hours ago | popularity 5 / 5 (1) | comments 0 | with audio podcast

Scientists uncover molecular roots of cocaine addiction in the brain

Researchers at Johns Hopkins have unraveled the molecular foundations of cocaine's effects on the brain, and identified a compound that blocks cravings for the drug in cocaine-addicted mice. The compound, already proven safe ...

Neuroscience created 15 hours ago | popularity not rated yet | comments 0 | with audio podcast

Hospitals profit when patients develop bloodstream infections

Johns Hopkins researchers report that hospitals may be reaping enormous income for patients whose hospital stays are complicated by preventable bloodstream infections contracted in their intensive care units.

Health created 11 hours ago | popularity not rated yet | comments 0

Researchers rewrite obsolete blood-ordering rules

Johns Hopkins researchers have developed new guidelines—the first in more than 35 years—to govern the amount of blood ordered for surgical patients. The recommendations, based on a lengthy study of blood use at The Johns ...

Surgery created 13 hours ago | popularity 4 / 5 (1) | comments 0

Genetic predictors of postpartum depression uncovered

Johns Hopkins researchers say they have discovered specific chemical alterations in two genes that, when present during pregnancy, reliably predict whether a woman will develop postpartum depression.

Psychology & Psychiatry created May 21, 2013 | popularity not rated yet | comments 0 | with audio podcast

'Doctor shopping' by obese patients negatively affects health

Overweight and obese patients are significantly more likely than their normal-weight counterparts to repeatedly switch primary care doctors, a practice that disrupts continuity of care and leads to more emergency room visits, ...

Overweight and Obesity created May 21, 2013 | popularity not rated yet | comments 0

New theory on genesis of osteoarthritis comes with successful therapy in mice

Scientists at Johns Hopkins have turned their view of osteoarthritis (OA) inside out. Literally. Instead of seeing the painful degenerative disease as a problem primarily of the cartilage that cushions joints, ...

Arthritis & Rheumatism created May 19, 2013 | popularity 4.9 / 5 (8) | comments 0 | with audio podcast

Despite new recommendations, women in 40s continue to get routine mammograms at same rate

Women in their 40s continue to undergo routine breast cancer screenings despite national guidelines recommending otherwise, according to new Johns Hopkins research.

Cancer created May 15, 2013 | popularity not rated yet | comments 0

Researchers discover dynamic behavior of progenitor cells in brain

By monitoring the behavior of a class of cells in the brains of living mice, neuroscientists at Johns Hopkins discovered that these cells remain highly dynamic in the adult brain, where they transform into ...

Neuroscience created May 09, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Restless legs syndrome, insomnia and brain chemistry: A tangled mystery solved?

Johns Hopkins researchers believe they may have discovered an explanation for the sleepless nights associated with restless legs syndrome (RLS), a symptom that persists even when the disruptive, overwhelming nocturnal urge ...

Neuroscience created May 07, 2013 | popularity 4.4 / 5 (5) | comments 1 | with audio podcast

Making cancer less cancerous: Blocking a single gene renders tumors less aggressive

Researchers at Johns Hopkins have identified a gene that, when repressed in tumor cells, puts a halt to cell growth and a range of processes needed for tumors to enlarge and spread to distant sites. The researchers hope that ...

Cancer created May 02, 2013 | popularity 4.7 / 5 (10) | comments 0 | with audio podcast

Going places: Rat brain 'GPS' maps routes to rewards

While studying rats' ability to navigate familiar territory, Johns Hopkins scientists found that one particular brain structure uses remembered spatial information to imagine routes the rats then follow. ...

Neuroscience created Apr 17, 2013 | popularity not rated yet | comments 0 | with audio podcast

Genes and their regulatory 'tags' conspire to promote rheumatoid arthritis, study finds

In one of the first genome-wide studies to hunt for both genes and their regulatory "tags" in patients suffering from a common disease, researchers have found a clear role for the tags in mediating genetic ...

Genetics created Jan 20, 2013 | popularity 4.6 / 5 (7) | comments 0 | with audio podcast

Elevated cadmium levels linked to disease

People with higher levels of cadmium in their urine—evidence of chronic exposure to the heavy metal found in industrial emissions and tobacco smoke—appear to be nearly 3.5 times more likely to die of liver disease than ...

Surgery created May 09, 2013 | popularity not rated yet | comments 0

Researchers discover new clues about how amyotrophic lateral sclerosis develops

Johns Hopkins scientists say they have evidence from animal studies that a type of central nervous system cell other than motor neurons plays a fundamental role in the development of amyotrophic lateral sclerosis (ALS), a ...

Neuroscience created Mar 31, 2013 | popularity 5 / 5 (4) | comments 0 | with audio podcast