Joslin Diabetes Center

Psychology & Psychiatry

Gut microbes may contribute to depression and anxiety in obesity

Like everyone, people with type 2 diabetes and obesity suffer from depression and anxiety, but even more so. Researchers at Joslin Diabetes Center now have demonstrated a surprising potential contributor to these negative ...

Cardiology

Cholesterol—Good for the brain, bad for the heart

Healthy brains need plenty of cholesterol for nerve cells to grow and work properly, but diabetes can reduce the amount of cholesterol in the brain, as a Joslin Diabetes Center team has demonstrated. Joslin researchers and ...

Health

Different sugars, different risks to your liver

If you're one of the two billion people in the world who are over-weight or obese, or the one billion people with fatty liver disease, your doctor's first advice is to cut calories—and especially to cut down on concentrated ...

Diabetes

Researchers uncover protective factor in diabetic eye disease

Researchers at Joslin Diabetes Center have shown that a protein found in the eye can protect against and potentially treat diabetic eye disease. At high enough levels, Retinol Binding Protein 3 (or RBP3) prevents the development ...

Alzheimer's disease & dementia

Insulin signaling failures in the brain linked to Alzheimer's disease

Scientists continue to find evidence linking Type 2 diabetes with Alzheimer's disease, the most common form of dementia and the seventh leading cause of death in the United States. However, little is understood about the ...

Medical research

Brown fat can burn energy in an unexpected way

When we are exposed to sufficient cold or exercise, small clusters of brown fat cells in our bodies begin to burn up energy. Since 2009, when researchers at Joslin Diabetes Center and other institutions discovered that this ...

Medical research

Researchers restore beta-cell function by deleting old cells

Research from Joslin Diabetes Center has shown in mice that insulin resistance increases the proportion of aged beta-cells which are dysfunction. Such an increase in aged beta-cells could lead to type 2 diabetes. These researchers ...

Diabetes

Solving a genetic mystery in type 1 diabetes

In type 1 diabetes, the immune system attacks the body's own insulin-producing cells. Scientists understand reasonably well how this autoimmune attack progresses, but they don't understand what triggers the attack or how ...

Medical research

Different kinds of white fat are important in disease

Excess white fat causes obesity, which in turn can drive diabetes and many other metabolic diseases that are growing at epidemic rates around the world. But all white fat is not born equal. For instance, "intra-abdominal" ...

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