Journal of Clinical Investigation

An autoimmune response may contribute to hypertension

High blood pressure is a major risk factor for heart attack, stroke, chronic heart failure, and kidney disease. Inflammation is thought to promote the development of high blood pressure, though it is not clear what triggers ...

Sep 17, 2014
popularity 5 / 5 (1) | comments 0

Mesothelial cells promote ovarian cancer metastasis

Less than half of the women diagnosed with ovarian cancer will survive beyond 5 years. Ovarian cancer readily spreads to abdominal organs, which are covered by a layer of cells called the mesothelium. Ovarian cancer cells ...

Sep 09, 2014
popularity 5 / 5 (1) | comments 0

Liver tropism is key for B cell deletion immunotherapy

Antibodies against the B cell surface protein CD20 have been used successfully to treat B cell-mediated autoimmune diseases and lymphomas. Antibody binding receptors, called Fc receptors, on other immune cells bind anti-CD20 ...

Nov 01, 2013
popularity not rated yet | comments 0