Journal of Clinical Investigation

Oncology & Cancer

Prostate cancer cells thrive on stress

Not surprisingly, a cancer diagnosis creates stress. And patients with prostate cancer show higher levels of anxiety compared to other cancer patients.

Oncology & Cancer

A new target in acute myeloid leukemia

Acute myeloid leukemia, a common leukemia in adults, is characterized by aberrant proliferation of cancerous bone marrow cells. Activating mutations in a protein receptor known as FLT3 receptor are among the most prevalent ...

Overweight & Obesity

Improving obesity-induced insulin sensitivity

In recent years, a growing body of evidence has linked inflammation to the development of insulin resistance. In insulin resistance, the hormone insulin is less effective in promoting glucose uptake from the bloodstream into ...

Overweight & Obesity

SORLA controls insulin signaling to promote obesity in mice

Large-scale genetic studies have linked variations in genes and proteins to an increased risk for developing obesity. Determining how these variations alter metabolism to increase body mass may lead to the identification ...

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