Gastrointestinal graft vs. host disease (GI-GVHD) is a life threatening complication that can occur after allogeneic hematopoietic cell transplantation, a procedure that is commonly used to treat patients with leukemia. There ...
May 5, 2016
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Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that affects multiple organ systems. Autoantibodies, which are produced by B cells, contribute to development of SLE. Recent studies have also shown that ...
May 5, 2016
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Patients with diabetes and metabolic syndrome are at increased risk of atherosclerosis and subsequent heart disease. It is not fully understood why atherosclerosis is increased with diabetes, but it has been proposed that ...
May 5, 2016
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Breast cancers are highly variable and the specific characteristics of a tumor determine treatment response and patient outcome. Genetic sequencing has improved our understanding of the genetic changes that underlie cancer ...
May 5, 2016
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Dilated cardiomyopathy (DCM) is a progressive thinning of heart muscle that commonly results in heart failure. DCM is a known secondary complication of conditions such as alcohol abuse and infection and is also an inherited ...
May 5, 2016
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Imaging probes that specifically target tumors can provide more sensitive and relevant information about the tumor compared to conventional, non-specific probes. Additionally, targeted probes can improve tumor detection, ...
May 5, 2016
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Following a heart attack, successful repair of damaged tissue can prevent cardiac rupture and other adverse outcomes. The ability to repair myocardial tissue depends on the activation of fibroblasts, which stimulate the formation ...
May 3, 2016
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Multiple myeloma (MM) is a hematological cancer that frequently acquires resistance to chemotherapeutic drugs. Additionally, many patients experience disease relapse, but these patients are difficult to treat as the cancer ...
Apr 21, 2016
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Rheumatoid arthritis (RA) is a debilitating autoimmune disorder that is characterized by the accumulation of inflammatory cells within the fluid of the joints. Current therapeutic strategies mostly serve to ease pain and ...
Apr 21, 2016
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Arrhythmogenic cardiomyopathy (ACM) is an inherited heart disease that results from mutations in genes that encode components of the cardiac desmosome, which forms the junction between cardiac muscle and the epithelium. Patients ...
Apr 21, 2016
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