A low platelet count can occur as the result of a variety of medical conditions and as a medication side effect. Platelet transfusion is often required for individuals with a critically low platelet level. Currently, the ...
May 11, 2015
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Bacterial meningitis is a life-threating infection of the central nervous system. Group B Streptococcus (GBS) is the leading cause of meningitis in newborn babies and can cause severe complications in those that survive the ...
May 11, 2015
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There are almost 40 million people throughout the world living with HIV-1/AIDs. While current antiretroviral therapies are able to reduce the amount of virus in the blood, HIV remains present in a latent state within T cells. ...
Mar 30, 2015
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Gliobststoma (GBM) is a highly aggressive brain tumor that is resistant to many conventional cancer therapies. The kinase mTOR induces pathways that are aberrantly activated in GBM. However, mTOR inhibitors have not shown ...
Mar 23, 2015
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Insulin resistance is a risk factor for developing both type 2 diabetes and cardiovascular disease. Almost one third of the U.S. population has some degree of insulin resistance, though it is undiagnosed in many of these ...
Mar 23, 2015
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As obesity rates rise, so does the incidence of type 2 diabetes (T2D). In obese individuals and those with obesity-induced T2D, there is an accumulation of immune cells within adipose tissue that results in a low level of ...
Mar 9, 2015
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Hematopoietic stem cells (HSCs) can differentiate into all of the different types of cells that comprise the blood and immune cell lineages. HSC transplantation is the only effective treatment for certain blood disorders; ...
Feb 9, 2015
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Type 1 diabetes is characterized by death and reduced function of β cells, which produce insulin. The presence of specific autoantibodies can identify individuals at risk of developing type 1 diabetes, and many of these ...
Feb 2, 2015
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The majority of lung cancers are classified as non-small cell lung cancer (NSCLC). Even with early detection, the 5-year survival rate for patients with NSCLC is less that 50%. Compared to the surrounding tissue, cancer cells ...
Jan 20, 2015
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Sepsis is a leading cause of death for patients in intensive care units. The excessive systemic inflammation in individuals with sepsis damages organs and can lead to death. Therapeutic options for sepsis are limited and ...
Jan 9, 2015
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