Journal of the National Cancer Institute
Estrogen plus progestin use linked with increased breast cancer incidence and mortality
Estrogen plus progestin use is linked with increased breast cancer incidence. In addition, prognosis is similar for both users and nonusers of combined hormone therapy, suggesting that mortality from breast cancer may be ...
Cancer
Mar 29, 2013 |
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Tumor boards linked to little association with effects on cancer care
There is little association of multidisciplinary tumor boards with measures of use, quality, or survival, and measuring only the presence of tumor boards may not be adequate in determining their effects on cancer care, according ...
Cancer
Dec 28, 2012 |
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PRT versus IMRT toxicity in Medicare beneficiaries with prostate cancer
There is no difference between proton radiotherapy (PRT) and intensity-modulated radiotherapy (IMRT) when comparing the toxicity among Medicare beneficiary patients with prostate cancer at 12 months post-treatment according ...
Cancer
Dec 17, 2012 |
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Folic acid, vitamins B6 and 12 do not affect colorectal adenoma risk
Combined folic acid, vitamin B6 and vitamin B12 supplements had no statistically significant effect on the risk of colorectal adenoma among women who were at high risk for cardiovascular disease, according to a study published ...
Cancer
Oct 12, 2012 |
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HIV drug shows efficacy in treating mouse models of HER2+ breast cancer
The HIV protease inhibitor, Nelfinavir, can be used to treat HER2-positive breast cancer in the same capacity and dosage regimen that it is used to treat HIV, according to a study published October 5 in the Journal of th ...
Cancer
Oct 06, 2012 |
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Probing the mechanism of ADAM28-mediated cancer metastasis
ADAM28, a metalloproteinase belonging to the ADAM gene family, cleaves the von Willebrand factor (VWF) and inhibits VWF-mediated cancer cell apoptosis, thereby enhancing lung metastases, so inhibiting its expression gives ...
Cancer
Jun 08, 2012 |
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Genetic variants, tobacco exposure and lung cancer risk
There is an association between the rs1051730-rs16969968 genotype and objective measures of tobacco exposure, which indicates that lung cancer risk is largely, if not entirely, mediated by level of tobacco exposure, according ...
Cancer
Apr 25, 2012 |
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DNA repair pathway score for predicting chemotherapy response in ovarian cancer patients
A DNA repair pathway-focused score has the potential to help determine if first-line platinum based chemotherapy can benefit advanced-stage ovarian cancer patients, according to a study published April 13 in the Journal of ...
Cancer
Apr 13, 2012 |
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Studies show exposure to diesel exhaust may increase lung cancer mortality
Heavy diesel exhaust (DE) exposure in humans may increase the risk of dying from lung cancer, according to two papers released March 2nd by the Journal of the National Cancer Institute.
Cancer
Mar 02, 2012 |
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Predicting the value of indexing symptoms for ovarian cancer
The use of symptom indices to identify patients with symptoms associated with ovarian cancer who may need further screening is increasing in both the UK and the US in an attempt to promote earlier diagnosis, but they may ...
Cancer
Jan 14, 2012 |
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Children and adolescent mobile phone users at no greater risk of brain cancer than non-users
Children and adolescents who use mobile phones are not at a statistically significant increased risk of brain cancer compared to their peers who do not use mobile phones, according to a study published July 27 in the Journal of ...
Health
Jul 27, 2011 |
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Barrett's esophagus carries lower risk of malignancy than previously reported
Patients with Barrett's esophagus may have a lower risk of esophageal cancer than previously reported, according to a large, long-term study published online June 16 in the Journal of the National Cancer Institute.
Cancer
Jun 16, 2011 |
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Quitlines help smokers quit regardless of recruitment method
Proactive telephone counseling helps smokers quit regardless of how they are recruited to a telephone quitline, according to a study published online June 10th in the Journal of the National Cancer Institute.
Health
Jun 11, 2011 |
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DNA repair system affects colon cancer recurrence and survival
Colorectal cancer patients with defects in mismatch repair--one of the body's systems for repairing DNA damage--have lower recurrence rates and better survival rates than patients without such defects, according to a study ...
Cancer
May 19, 2011 |
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Patient reports of relatives' cancer history often not accurate
Doctors often rely on a patient's knowledge of family medical history to estimate his or her risk of cancer. However, patient reports of family cancer history are not highly accurate, according to a study appearing May 11th ...
Cancer
May 11, 2011 |
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