Ludwig Institute for Cancer Research

Mapping the embryonic epigenome

A large, multi-institutional research team involved in the NIH Epigenome Roadmap Project has published a sweeping analysis in the current issue of the journal Cell of how genes are turned on and off to direct early human ...

Genetics created May 09, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Molecular switch identified that controls key cellular process

The body has a built-in system known as autophagy, or 'self-eating,' that controls how cells live or die. Deregulation of autophagy is linked to the development of human diseases, including neural degeneration and cancer.

Medical research created Aug 01, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

How the tilt of a cell-surface receptor prevents cancer

Clear communication between cells is essential to every aspect of the body's internal function. But since cells can't talk, or send emails, how do they communicate?

Cancer created Jan 31, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Epigenetic marker 5hmC opens door to studying its role in developmental disorders and disease

Nearly every cell in the human body carries a copy of the full human genome. So how is it that the cells that detect light in the human eye are so different from those of, say, the beating heart or the spleen?

Genetics created Feb 04, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Novel combination therapy shuts down escape route, killing glioblastoma tumor cells

Glioblastoma, the most common and lethal form of brain tumor in adults, is challenging to treat because the tumors rapidly become resistant to therapy. As cancer researchers are learning more about the causes of tumor cell ...

Cancer created Feb 26, 2013 | popularity 5 / 5 (1) | comments 2 | with audio podcast