Massachusetts General Hospital
Deeper view of HIV reveals impact of early mutations
Mutations in HIV that develop during the first few weeks of infection may play a critical role in undermining a successful early immune response, a finding that reveals the importance of vaccines targeting regions of the ...
HIV & AIDS
Mar 08, 2012 |
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Experimental drug reduces cortisol levels, improves symptoms in Cushing's disease
A new investigational drug significantly reduced urinary cortisol levels and improved symptoms of Cushing's disease in the largest clinical study of this endocrine disorder ever conducted. Results of the clinical trial conducted ...
Medical research
Mar 07, 2012 |
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Diabetes drug halts atherosclerosis progression in HIV-infected patients
Treatment with the common diabetes drug metformin appears to prevent progression of coronary atherosclerosis in patients infected with HIV. In a presentation today at the 19th Conference on Retroviruses and Opportunistic ...
HIV & AIDS
Mar 07, 2012 |
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Study reveals how anesthetic isoflurane induces Alzheimer's-like changes in mammalian brains
The association of the inhaled anesthetic isoflurane with Alzheimer's-disease-like changes in mammalian brains may by caused by the drug's effects on mitochondria, the structures in which most cellular energy is produced. ...
Neuroscience
Mar 01, 2012 |
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Study finds HIV-specific CD4 cells that control viral levels
A subpopulation of the immune cells targeted by HIV may play an important role in controlling viral loads after initial infection, potentially helping to determine how quickly infection will progress. In the February 29 issue ...
HIV & AIDS
Feb 29, 2012 |
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Scientists isolate egg-producing stem cells from adult human ovaries
For the first time, Massachusetts General Hospital (MGH) researchers have isolated egg-producing stem cells from the ovaries of reproductive age women and shown these cells can produce what appear to be normal egg cells or ...
Medical research
Feb 26, 2012 |
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Study finds some insulin production in long-term Type 1 diabetes
Massachusetts General Hospital (MGH) research has found that insulin production may persist for decades after the onset of type 1 diabetes. Beta cell functioning also appears to be preserved in some patients years after apparent ...
Diabetes
Feb 21, 2012 |
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Potential treatment target for KRAS-mutated colon cancer found
Researchers from the Massachusetts General Hospital (MGH) Cancer Center have identified a new potential strategy for treating colon tumors driven by mutations in the KRAS gene, which usually resist both conventional and targeted ...
Cancer
Feb 16, 2012 |
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Vitamin D treatment not found to reduce cardiovascular abnormalities in kidney disease patients
Almost a year's treatment with a vitamin D compound did not alleviate key structural and functional cardiovascular abnormalities in patients with kidney disease and cardiac enlargement. In a paper in the February 15 Journal of ...
Cardiology
Feb 14, 2012 |
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Blood test accurately distinguishes depressed patients from healthy controls
The initial assessment of a blood test to help diagnose major depressive disorder indicates it may become a useful clinical tool. In a paper published in the journal Molecular Psychiatry, a team including Massachusetts Genera ...
Psychology & Psychiatry
Feb 01, 2012 |
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Study defines a new genetic subtype of lung cancer
A report from investigators at the Massachusetts General Hospital (MGH) Cancer Center has defined the role of a recently identified gene abnormality in a deadly form of lung cancer. Tumors driven by rearrangements in the ...
Cancer
Jan 31, 2012 |
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Color-coding, rearranging food products improves healthy choices in hospital cafeteria
A simple program involving color-coded food labeling and adjusting the way food items are positioned in display cases was successful in encouraging more healthful food choices in a large hospital cafeteria. ...
Health
Jan 19, 2012 |
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Novel gene mutations associated with bile duct cancer
Investigators at the Massachusetts General Hospital (MGH) Cancer Center have identified a new genetic signature associated with bile duct cancer, a usually deadly tumor for which effective treatment currently is limited. ...
Cancer
Jan 18, 2012 |
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Researchers find novel way to prevent drug-induced liver injury
Massachusetts General Hospital (MGH) investigators have developed a novel strategy to protect the liver from drug-induced injury and improve associated drug safety. In their report receiving advance online publication in ...
Medical research
Jan 15, 2012 |
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Newly identified type of immune cell may be important protector against sepsis
Investigators in the Massachusetts General Hospital (MGH) Center for Systems Biology have discovered a previously unknown type of immune cell, a B cell that can produce the important growth factor GM-CSF, ...
Immunology
Jan 12, 2012 |
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