Massachusetts Institute of Technology

Neuroscience

How cognition changes before dementia hits

Individuals with mild cognitive impairment, especially of the "amnestic subtype" (aMCI), are at increased risk for dementia due to Alzheimer's disease relative to cognitively healthy older adults. Now, a study co-authored ...

Oncology & Cancer

How early-stage cancer cells hide from the immune system

One of the immune system's primary roles is to detect and kill cells that have acquired cancerous mutations. However, some early-stage cancer cells manage to evade this surveillance and develop into more advanced tumors.

Medications

New model identifies drugs that shouldn't be taken together

Any drug that is taken orally must pass through the lining of the digestive tract. Transporter proteins found on cells that line the GI tract help with this process, but for many drugs, it's not known which of those transporters ...

Oncology & Cancer

Hitchhiking cancer vaccine makes progress in the clinic

Therapeutic cancer vaccines are an appealing strategy for treating malignancies. In theory, when a patient is injected with peptide antigens—protein fragments from mutant proteins only expressed by tumor cells—T cells ...

Neuroscience

Scientists develop low-cost device to make cell therapy safer

A tiny device built by scientists at MIT and the Singapore-MIT Alliance for Research and Technology could be used to improve the safety and effectiveness of cell therapy treatments for patients suffering from spinal cord ...

Sports medicine & Kinesiology

New model predicts how shoe properties affect a runner's performance

A good shoe can make a huge difference for runners, from career marathoners to couch-to-5K first-timers. But every runner is unique, and a shoe that works for one might trip up another. Outside of trying on a rack of different ...

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