Ohio State University Medical Center
Patient's own immune cells may blunt viral therapy for brain cancer
Doctors now use cancer-killing viruses to treat some patients with lethal, fast-growing brain tumors. Clinical trials show that these therapeutic viruses are safe but less effective than expected.
Cancer
Nov 25, 2012 |
3.7 / 5 (3) |
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Inherited DNA change explains overactive leukemia gene
A small inherited change in DNA is largely responsible for overactivating a gene linked to poor treatment response in people with acute leukemia.
Genetics
May 25, 2012 |
5 / 5 (1) |
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Big data analysis identifies prognostic RNA markers in a common form of breast cancer
A Big Data analysis that integrates three large sets of genomic data available through The Cancer Genome Atlas has identified 37 RNA molecules that might predict survival in patients with the most common form of breast cancer.
Cancer
Apr 29, 2013 |
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New agent might control breast-cancer growth and spread
A new study led by researchers at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) suggests that an unusual ...
Cancer
Apr 22, 2013 |
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Small molecules in the blood might gauge radiation effects after exposure
Ohio State University cancer researchers have identified molecules in the bloodstream that might accurately gauge the likelihood of radiation illness after exposure to ionizing radiation.
Cancer
Feb 25, 2013 |
5 / 5 (1) |
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Triple-negative breast cancer subtypes identified using microRNA
A new, large-scale study of triple-negative breast cancer shows that small molecules called microRNA can be used to define four subtypes of this aggressive malignancy.
Cancer
Feb 07, 2013 |
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Older and younger chronic leukemia patients may need different therapy
Doctors should use different therapies when treating older and younger patients with chronic lymphocytic leukemia, according to a new study led by researchers at the Ohio State University Comprehensive Cancer Center – Arthur ...
Cancer
Dec 12, 2012 |
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Reduced intensity regimen prior to marrow transplant better for older leukemia patients
A new study led by researchers at the Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) shows that preparing older acute myeloid ...
Cancer
Dec 10, 2012 |
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Possible therapy for tamoxifen resistant breast cancer identified
(Medical Xpress)—A study by researchers at the Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) has discovered how tamoxifen-resistant ...
Cancer
Aug 30, 2012 |
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Liver cancer cells stop making glucose as they become cancerous
As liver cancer develops, tumor cells lose the ability to produce and release glucose into the bloodstream, a key function of healthy liver cells for maintaining needed blood-sugar levels.
Cancer
Jul 30, 2012 |
5 / 5 (1) |
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miR-122: Loss of tiny liver molecule might lead to liver cancer
A new study shows that loss of a small RNA molecule in liver cells might cause liver cancer and that restoring the molecule might slow tumor growth and offer a new way to treat the disease.
Medical research
Jul 23, 2012 |
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Study reveals new mechanism that might promote cancer's growth and spread in the body
Researchers have discovered a previously unknown mechanism that promotes the growth and spread of cancer. The mechanism involves key immune cells and a new role for small regulatory molecules called microRNA. The findings ...
Cancer
Jul 10, 2012 |
4.5 / 5 (2) |
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miR loss may power maligant transformation in chronic leukemia
Loss of a particular microRNA in chronic lymphocytic leukemia shuts down normal cell metabolism and turns up alternative mechanisms that enable cancer cells to produce the energy and build the molecules they need to proliferate ...
Cancer
Jul 05, 2012 |
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Inhibitors of shuttle molecule show promise in acute leukemia
A novel family of experimental agents that blocks a molecule from shuttling proteins out of the cell nucleus might offer a new treatment for people with acute leukemia, according to a study by researchers at the Ohio State ...
Cancer
Jun 19, 2012 |
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Marker distinguishes more-aggressive from less-aggressive forms of chronic leukemia
Researchers have identified a prognostic marker in the most common form of chronic leukemia that can help to distinguish which patients should start treatment quickly from those who can safely delay treatment, perhaps for ...
Cancer
Jun 12, 2012 |
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