RIKEN

Immunology

Researchers uncover origin of virus-fighting plasma B cells

Plasma B cells, which move through the body releasing antibodies, are an important component of the body's fight against viral infections and other invaders. They are relatively rare, however, and increasing their ranks is ...

Neuroscience

The brain's GPS has a buddy system

To be successful as a social animal, you need to know where you stand relative to others. Brain cells that perform precisely this function—locating the 'self' and others in space—have now been identified. In rats, the ...

Neuroscience

What's that smell? The advantage of sniffing

Researchers led by Takeshi Imai at the RIKEN Center for Developmental Biology (CDB) have discovered how the physical and sensory perceptions associated with sniffing are kept separate and why sniffing can help identify odors, ...

Neuroscience

Elementary neural processing units that tile the mouse brain

A hexagonal lattice organizes major cell types in the cerebral cortex, researchers in Japan have discovered. The pattern repeats across the brain, with similar cells synchronizing their activity in 'microcolumns', which could ...

Neuroscience

Moving neuroscience into the fast lane

At the RIKEN Brain Science Institute in Japan, a two-year project from Andrea Benucci's research group has culminated in the construction and deployment of a high-throughput system to study mouse behavior and physiology. ...

Oncology & Cancer

Blocking key pathways is a way to defeat cancer stem cells

Scientists from the RIKEN Center for Integrative Medical Sciences in Japan and international collaborators have found that in humanized mice, a cocktail of drugs blocking certain key pathways is effective in eliminating acute ...

Immunology

Activation of immune T cells leads to behavioral changes

Scientists from the RIKEN Center for Integrative Medical Sciences in Japan and collaborators have found that T cells—immune cells that help to protect the body from infections and cancer—change the body's metabolism when ...

Oncology & Cancer

Halting liver cancer with a sugar look-a-like

Researchers at the RIKEN Global Research Cluster in Japan have discovered a way to prevent the spread of cancer in the liver. Published in the journal Cell Chemical Biology, the study details how treatment with a modified ...

Neuroscience

Learning and unlearning to fear: The two faces of noradrenaline

Emotional learning can create strong memories and powerful emotional responses, but flexible behavior demands that these responses be inhibited when they are no longer appropriate. Scientists at the RIKEN Brain Science Institute ...

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