RIKEN

Scanning for health and disease

Many mysteries still surround the human body. In particular, the molecular and cellular processes of the body's systems and organs, and their occasional malfunctions, remain largely unobserved at the macroscale. ...

Oct 03, 2014
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Waking up the visual system

The ways that neurons in the brain respond to a given stimulus depends on whether an organism is asleep, drowsy, awake, paying careful attention or ignoring the stimulus. However, while the properties of ...

Oct 03, 2014
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Broken signals lead to neurodegeneration

Researchers from the RIKEN Brain Science Institute in Japan, in collaboration with Juntendo University and the Japan Science and Technology Agency, have discovered that a cell receptor widely involved in intracellular ...

Sep 08, 2014
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Steering the filaments of the developing brain

During brain development, nerve fibers grow and extend to form brain circuits. This growth is guided by molecular cues (Fig. 1), but exactly how these cues guide axon extension has been unclear. Takuro Tojima ...

Aug 01, 2014
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In the gut, immunity is a two-way street

In recent years, it has become increasingly clear that many diseases are triggered or maintained by changes in bacterial communities in the gut. However, the general view up into now has been rather simple: bacteria stimulate ...

Jul 10, 2014
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Dying cells trigger immunity

The immune system produces various types of immune cells—some are pre-programmed to target pathogens that the immune system has previously encountered, while others are 'naive' and retain the ability to ...

May 30, 2014
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