Rockefeller University
Bacteria enter via mucus-making gut cells
Cells making slippery mucus provide a sticking point for disease-causing bacteria in the gut, according to a study published on October 3 in the Journal of Experimental Medicine.
Diseases, Conditions, Syndromes
Oct 03, 2011 |
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Tumor environment keeps tumor-fighting T cells away
Tumors have an arsenal of tricks to help them sidestep the immune system. A study published on September 19 in the Journal of Experimental Medicine reveals a new trick -- the ability to keep tumor-fighting T cells out by ...
Cancer
Sep 19, 2011 |
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New perspectives on sensory mechanisms
The latest Perspectives in General Physiology series examines the mechanisms of visual, aural, olfactory, and tactile processes that inform us about the environment. The series appears in the September 2011 ...
Medical research
Aug 29, 2011 |
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Scientists identify broad and potent HIV antibodies that mimic CD4 binding
In a finding that may be good news for scientists developing HIV vaccines and therapies, a team of researchers at The Rockefeller University and the Howard Hughes Medical Institute have found a way to investigate ...
HIV & AIDS
Jul 20, 2011 |
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AMPK amplifies Huntington's disease
A new study describes how hyperactivation of AMP-activated protein kinase (AMPK) promotes neurodegeneration in Huntington's disease (HD). The article appears online on July 18, 2011, in The Journal of Cell Biology.
Medical research
Jul 18, 2011 |
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SUMO defeats protein aggregates that typify Parkinson's disease
A small protein called SUMO might prevent the protein aggregations that typify Parkinson's disease (PD), according to a new study in the July 11, 2011, issue of The Journal of Cell Biology.
Parkinson's & Movement disorders
Jul 11, 2011 |
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Decoding chronic lymphocytic leukemia
A paper published online on June 13 in the Journal of Experimental Medicine identifies new gene mutations in patients with chronic lymphocytic leukemia (CLL) -- a disease often associated with lack of response to chemotherapy and po ...
Cancer
Jun 13, 2011 |
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Scientists create first genetically humanized mouse model for hepatitis C
Scientists at Rockefeller University and The Scripps Research Institute have developed the first genetically humanized mouse model for hepatitis C, an achievement that will enable researchers to test molecules that block ...
Medical research
Jun 08, 2011 |
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Noncoding RNA may promote Alzheimer's disease
Researchers pinpoint a small RNA that spurs cells to manufacture a particular splice variant of a key neuronal protein, potentially promoting Alzheimer's disease (AD) or other types of neurodegeneration. The ...
Medical research
May 30, 2011 |
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Researchers explain how animals sense potentially harmful acids
All animals face the challenge of deciding which chemicals in the environment are useful and which are harmful. A new study greatly improves our understanding of how animals sense an important class of potentially ...
Medical research
May 16, 2011 |
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Analysis of sperm differentiation reveals new mode of proteasome regulation
(Medical Xpress) -- Early in development, cells undergo a controlled demolition that helps to shape their raw, pliable material into the specialized forms they must have to do their jobs as adults. The process ...
Medical research
May 02, 2011 |
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Ibuprofen, aspirin, other anti-inflammatory drugs reduce effectiveness of SSRI antidepressants
Scientists at the Fisher Center for Alzheimer's Disease Research at The Rockefeller University, led by Paul Greengard, Ph.D., and Jennifer Warner-Schmidt, Ph.D., have shown that anti-inflammatory drugs, which include ibuprofen, ...
Medications
Apr 25, 2011 |
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Big picture of how interferon-induced genes launch antiviral defenses revealed
When viruses attack, one molecule more than any other fights back. Interferon triggers the activation of more than 350 genes, and despite the obvious connection, the vast majority have never been tested for antiviral properties. ...
Medical research
Apr 10, 2011 |
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