Rockefeller University
Researchers create map of 'shortcuts' between all human genes
Some diseases are caused by single gene mutations. Current techniques for identifying the disease-causing gene in a patient produce hundreds of potential gene candidates, making it difficult for scientists to pinpoint the ...
Genetics
Mar 18, 2013 |
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Brain displays an intrinsic mechanism for fighting infection
(Medical Xpress)—White blood cells have long reigned as the heroes of the immune system. When an infection strikes, the cells, produced in bone marrow, race through the blood to fight off the pathogen. ...
Medical research
Nov 19, 2012 |
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Potent antibodies neutralize HIV and could offer new therapy, study finds
(Medical Xpress)—Having HIV/AIDS is no longer a death sentence, but it's still a lifelong illness that requires an expensive daily cocktail of drugs—and it means tolerating those drugs' side effects and ...
Immunology
Nov 07, 2012 |
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Sweat glands grown from newly identified stem cells
To date, few fundamentals have been known about the most common gland in the body, the sweat glands that are essential to controlling body temperature, allowing humans to live in the world’s diverse climates. ...
Medical research
Jul 06, 2012 |
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Ibuprofen, aspirin, other anti-inflammatory drugs reduce effectiveness of SSRI antidepressants
Scientists at the Fisher Center for Alzheimer's Disease Research at The Rockefeller University, led by Paul Greengard, Ph.D., and Jennifer Warner-Schmidt, Ph.D., have shown that anti-inflammatory drugs, which include ibuprofen, ...
Medications
Apr 25, 2011 |
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Scientists discover gene mutation that causes children to be born without spleen
The spleen is rarely noticed, until it is missing. In children born without this organ, that doesn't happen until they become sick with life-threatening bacterial infections. An international team of researchers led by scientists ...
Genetics
Apr 11, 2013 |
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Scientists use nature against nature to develop an antibiotic with reduced resistance
A new broad range antibiotic, developed jointly by scientists at The Rockefeller University and Astex Pharmaceuticals, has been found to kill a wide range of bacteria, including drug-resistant Staphylococcus (MRSA) bacter ...
Medications
Apr 10, 2013 |
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Mechanism of mutant histone protein in childhood brain cancer revealed
(Medical Xpress)—Most cancer treatments are blunt. In an attempt to eradicate tumors, oncologists often turn to radiation or chemotherapy, which can damage healthy tissue along with the cancerous growths. ...
Cancer
Apr 01, 2013 |
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Protein family linked to autism suppresses the development of inhibitory synapses
Synapse development is promoted by a variety of cell adhesion molecules that connect neurons and organize synaptic proteins. Many of these adhesion molecules are linked to neurodevelopmental disorders; mutations ...
Medical research
Jan 28, 2013 |
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Stay-at-home transcription factor prevents neurodegeneration
A study in The Journal of Cell Biology shows how a transcription factor called STAT3 remains in the axon of nerve cells to help prevent neurodegeneration. The findings could pave the way for future drug therapies to slow ...
Medical research
Oct 29, 2012 |
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Protein proves to be vital in immune response to bacteria
(Medical Xpress) -- A team of researchers led by scientists at Rockefeller University have discovered that a protein once thought to be mainly involved in antiviral immunity is in fact more important in ...
Medical research
Aug 13, 2012 |
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Collaboration finds kidney disease tied to DNA damage
(Medical Xpress) -- A research collaboration involving Rockefeller University and more than two dozen other institutions has found a link between a gene mutation and chronic kidney failure. The study, published ...
Genetics
Aug 09, 2012 |
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Starr collaboration illuminates mysterious pathway to immortality in cancer cells
(Medical Xpress) -- Cancer cells are immortal because they circumvent failsafe mechanisms that stop out-of-control cell proliferation. One of these mechanisms – the progressive shortening of chromosomes ...
Cancer
Jul 25, 2012 |
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Rockefeller scientists pioneer new method to determine mechanisms of drug action
(Medical Xpress) -- Knowing that a drug works is great. Knowing how it works is a luxury. And until now, determining a drug’s mechanism of action has been a tedious and difficult process for scientists.
Medical research
May 25, 2012 |
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Influenza 'histone mimic' suppresses antiviral response
(Medical Xpress) -- For a virus like influenza, the key to success isn't in overpowering the immune system, it’s in tricking it. A team of researchers led by scientists at The Rockefeller University has ...
Medical research
Mar 14, 2012 |
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