Rockefeller University

Alzheimer's disease & dementia

'Exhausted' immune cells may drive Alzheimer's

Mice reach the twilight of their lives at around age two, the rough equivalent of 80 in human years. And when researchers introduce specific mutations into mice and then age them up, the mice can grow forgetful and irritable—eventually ...

Neuroscience

New method tracks how brain cells age

Hospital nurseries routinely place soft bands around the tiny wrists of newborns that hold important identifying information such as name, sex, mother, and birth date. Researchers at Rockefeller University are taking the ...

Medications

Unlocking how the new Alzheimer's drug lecanemab works

Approved by the FDA earlier this year, the Alzheimer's therapy lecanemab is an antibody that reduces the buildup in the brain of a sticky peptide called amyloid-beta (Aβ), which is thought to be a main driver of the disease. ...

Diseases, Conditions, Syndromes

An immune flaw may cause West Nile virus's deadliest symptoms

Four out of five of people infected with the mosquito-borne West Nile virus (WNV) won't even know it—heartening news when you consider there's no vaccine to prevent the disease nor targeted medications to treat it. However, ...

Oncology & Cancer

Proteome of rare liver cancer sheds new light on basic biology

Doctors have long puzzled over a mystery at the heart of fibrolamellar carcinoma, a rare and deadly liver cancer that mainly affects children and young adults. Like more common liver cancers, and liver failure itself, fibrolamellar ...

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