Salk Institute

Oncology & Cancer

Mysterious tuft cells found to play role in pancreatitis

Persistent inflammation of the pancreas (chronic pancreatitis) is a known risk factor for developing pancreatic cancer, the third-deadliest cancer in the United States. Tuft cells—cells sensitive to chemical (chemosensory) ...

Genetics

Scientists link rapid brain growth in autism to DNA damage

Researchers at the Salk Institute have discovered a unique pattern of DNA damage that arises in brain cells derived from individuals with a macrocephalic form of autism spectrum disorder (ASD). The observation, published ...

Alzheimer's disease & dementia

Alzheimer's drug candidates reverse broader aging, study shows

In mouse models of Alzheimer's disease, the investigational drug candidates known as CMS121 and J147 improve memory and slow the degeneration of brain cells. Now, Salk researchers have shown how these compounds can also slow ...

Medical research

Diabetes drug has unexpected, broad implications for healthy aging

Metformin is the most commonly prescribed type 2 diabetes drug, yet scientists still do not fully know how it works to control blood sugar levels. In a collaborative effort, researchers from the Salk Institute, The Scripps ...

Neuroscience

Brain biomarker predicts compulsive drinking in mice

Although alcohol use is ubiquitous in modern society, only a portion of individuals develop alcohol use disorders or addiction. Yet, scientists have not understood why some individuals are prone to develop drinking problems, ...

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